OG'IZ BO'SHLIG'I KO’P SHAKLLI EKSUDATIV ERITEMASINING MIKROBIOLOGIK VA IMMUNOLOGIK XUSUSIYATLARI
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ko’p shaklli ekssudativ eritema, mahalliy davolash, takomillashtirish, qiyosiy o'rganish, fotodinamik terapiya, og'iz shilliq qavati##article.abstract##
Ushbu tadqiqot an'anaviy terapiyani fotodinamik terapiya (FDT) yordamida lazer nurlanishini qo'shish bilan solishtirish orqali ko’p shaklli ekssudativ eritema (KSHEE) bilan og'rigan bemorlarni davolashni takomillashtirishga qaratilgan. Tadqiqotda KSHEE bilan o’g’rigan jami 64 nafar bemor ishtirok etdi va ularning klinik ko’rinishi va og'iz shilliq qavatining shikastlanishi uchun xavf omillari tahlil qilindi. Asosiy guruh lidokain geli, xlorheksidin eritmasi va PDTni o'z ichiga olgan mahalliy va umumiy muolajalarni oldi, taqqoslash guruhi esa an'anaviy davolashni oldi. Terapiyaning samaradorligi sub'ektiv hislar va klinik belgilarga asoslangan 3 ballli tizim yordamida baholandi. Davolash paytida hech qanday nojo'ya ta'sirlar yoki asoratlar aniqlanmadi. Natijalar shuni ko'rsatdiki, asosiy guruhdagi bemorlar taqqoslash guruhidagi bemorlarga nisbatan KSHEE ning klinik ko'rinishlarida sezilarli pasayish kuzatilgan. Semptomlarning o'rtacha intensivligi asosiy guruhda 5- kunida qariyb 2 marta va 15-kunida 11 martadan ko'proq kamaydi, taqqoslash guruhida esa pasayish mos ravishda 4 marta va 8 martani tashkil etdi. Ushbu topilmalar davolash rejimiga FDT yordamida lazer nurlanishining qo'shilishi ekssudativ eritema multiforme bilan og'rigan bemorlarning natijalarini yaxshilashi mumkinligini ko'rsatadi.
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