O’TKIR UCHLI KONDILOMALARDA IMIKVIMOD KREMINI SAMARADORLIGI
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o’tkir uchli kondiloma, TLR retseptorlar, qaytalanish chastotasi. monoterapiya, inson papillomavirusi, virusli infektsiyalar, hujayra immuniteti##article.abstract##
O’tkir uchli kondilomalar odam papilloma virusi keltirib chiqaradigan, jinsiy yo’l orqali yuquvchi kasallikdir va dunyo bo’ylab yoshlar orasida keng tarqalgan. Davolashda qo’llaniladigan mahalliy dorilar (podoksilifilin, interferon) va sitodestruktiv usullar o’rtacha samaradorlikni ko’rsatmoqda va qaytalanish darajasi yuqori bo’lib qolmoqda. Ushbu tadqiqotda ikkita davolash usulini taqqoslash uchun monoterapiyani lazer yordamida o’tkir uchli kondilomalarni olib tashlab, kompleks davo uchun anogenital so’gallar olingan joyiga 12 hafta davomida 5% Imikvimod kremini surtish tavsiya qilingan. 6 oylik kuzatuv natijasida 1-guruhdagi 28 (37,3%) nafar bemorlarda qaytalanishlar kuzatilgan. 2-guruh bemorlarda 6 oy ichida qaytalanish chastotasi faqat 9 ta (7,2%) bo’lgan va klinik yahshilanish 116 (92,8%) tani tashkil qilgan.
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