NORMAL JOYLASHGAN YOʻLDOSH MUDDATIDAN OLDIN KOʻCHISHIDA YOʻLDOSH TOʻQIMASINI OʻRGANISHDA ZAMONAVIY KLINIK VA MORFOLOGIK YONDASHUVLAR
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yo‘ldoshning muddatidan oldin ajralishi, platsenta, platsenta patologiyasi, morfometriya##article.abstract##
Tadqiqot maqsadi. Yo‘ldoshning muddatidan oldin ajralishida platsenta to‘qimasida yuzaga keladigan klinik, morfologik, makroskopik, mikroskopik, morfometrik hamda immunogistokimyoviy o‘zgarishlarni kompleks baholash. Material va usullar. Tadqiqotda tug‘ruqdan keyin olingan 157 ta platsenta tekshirildi. Asosiy guruhni yo‘ldoshning muddatidan oldin ajralishi kuzatilgan 127 nafar ayol, nazorat guruhini esa fiziologik homiladorlik va asoratsiz tug‘ruq kechirgan 30 nafar ayol tashkil etdi. Klinik tekshiruv, makroskopik va organometrik baholash, gistologik tekshiruv, morfometriya Natijalar. Makroskopik tekshiruvda platsenta massasining kamayishi, retroplatsentar gematomalar, ishemik infarktlar va qon tomir tizimidagi yaqqol o‘zgarishlar aniqlandi. Mikroskopik tekshiruv xorion vorsinkalari tomirlarining trombozi, qon tomir devorining fibrinoid nekrozi, vorsinkalar arxitektonikasining buzilishi va surunkali platsentar yetishmovchilik belgilarini ko‘rsatdi. Morfometrik tahlilda funksional vorsinkalar o‘lchamining kamayishi hamda sinsitiokapillyar membrana qalinligining ortishi qayd etildi. Xulosa. Klinik, morfologik, morfometrik va immunogistokimyoviy usullarni kompleks qo‘llash yo‘ldoshning muddatidan oldin ajralishida platsenta to‘qimasidagi strukturaviy va funksional o‘zgarishlarni obyektiv baholash imkonini beradi hamda platsentar disfunksiyani tashxislash va noqulay akusherlik hamda perinatal natijalarni prognozlash samaradorligini oshiradi.
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