CURRENT ISSUES OF ACUCHERY-NEUROLOGICAL COMPORTANCE OF PREGNANT WITH EPILEPSIA
Keywords:
epilepsy, pregnancy, anti-epileptic drugs, teratogenicity, multidisciplinary management, maternal outcomes, perinatal outcomes, preconceptional counseling, folic acid, neurodevelopment, therapeutic monitoring, obstetric complications, prenatal diagnosticsAbstract
Epilepsy is one of the most common chronic neurological diseases affecting approximately 65 million people worldwide. Among women of reproductive age, the prevalence of epilepsy is 0.3-0.8%, which corresponds to approximately 1.1 million women of childbearing age in Europe alone. Every year, more than 1.2 million pregnancies are registered in women with epilepsy worldwide, which is 0.3-0.5% of the total number of births. Pregnancy in women with epilepsy is a unique medical situation characterized by a complex interaction between epileptic seizures, anti- epileptic therapy, physiological changes in pregnancy, and fetal development. This problem requires an integrated approach involving a multidisciplinary team of specialists, including obstetrician-gynecologists, neurologist-epileptologists, clinical pharmacologists, geneticists, neonatologists, and child development specialists.
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