TAUSIN PREPARATI GEPATOPROTEKTOR XUSUSIYATLARINI O’RGANISH
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gepatotoksik ta’sir, gepatoprotektiv ta’sir, kalamushlar, paratsetamol, sink diaspartat, tausin birikmasi##article.abstract##
Ushbu maqolada kalamush jigarida tausin preparatining gepatoprotektor xususiyatlarini o’rgangan olimlarning so’nggi tadqiqotlari tahlili keltirilgan. Таурин обладает умеренным положительным инотропным действием и способствует натриурезу и диурезу. Хотя недавние исследования показали улучшение переносимости физических нагрузок у пациентов, принимающих таурин [17], остается неизвестным, снижает ли таурин риск в общей популяции. Кроме того, вопрос о снижении смертности пациентов, принимающих таурин, не изучался. Есть основания полагать, что таурин может увеличить продолжительность жизни пациентов
Библиографические ссылки
Katzung B.G. Basic and clinical pharmacology T. 1. Moscow: "Binom", St. Petersburg: "Dialect"; 2008.
Mashkovsky M.D. Medicines. Moscow: New wave; 2005.
Acharya M. Comparison of the protective effects of N-acetylcysteine, hypotaurine and taurine against acetaminophen-induced hepatotoxicity in rats. J. Biomed. scientific 2010; 24:31–3.
Pashko A.Yu., Borisenok O.A., Bushma M.I. Taucine correction of metabolic disorders in the liver and organ function in rats with paracetamol intoxication. Toxicological Bulletin. 2015, pp. 42-45.
Rebrova O.Yu. Statistical analysis of medical data. Moscow: MediaSphere; 2002.
James L.P. [et al.] Pharmacokinetics of acetaminophen-protein adducts in adults with acetaminophen overdose and acute liver failure. Drag Metab Dispos. 2009; 37:1779-84.
Sheibak V.M., Sheibak L.N. The biological role of taurine in the body of mammals. Medical news. 2005; 10:65-15.
But-Gusaim L.St., Gerashchenko N.V., Bloshko T.E. Prospects for the use of zinc preparations in perinatology. Materials of the scientific-practical conference dedicated to 60 years of the ambulance service and 10 years of the GKO SMP. September 5-7, 2005. Grodno: GrGMU; 2005.
Truong-Tran A.K. other. The role of zinc in caspase activation and apoptotic cell death. Biometals. 2001; 14:315–330.
Schumann G. et al. IFCC Primary Reference Procedures for the Measurement of Enzyme Catalytic Activity Concentrations at 37°C. Part 3. Reference procedure for measuring the catalytic concentration of lactate dehydrogenase. wedge. chem. laboratory Med. 2002; 40:643-648.
Kamyshnikov V.S. Handbook of clinical and biochemical laboratory diagnostics T. 2. Minsk: "Belarus"; 2002.
Harada H. et al. Oral taurine prevents the development of ethanol-induced hypertension in rats. Hypertension res. 2000; 23:277–284.
Formigari A, Irato P, Santon A. Zinc, antioxidant systems and metallothionein in metal-mediated apoptosis: biochemical and cytochemical aspects. Comp. Biochem. Physiol. Fri. S. 2007; 146:443–459.
Pashko A.Yu., Bushma K.M., Borisenok O.A., Bushma M.I. Correction of hepatotoxicity indicators in plasma of rats with cholestasis with the drug "taucine". Toxicological Bulletin. 2015, pp. 12-15.
Shaffer S.V., Shimada-Takaura K., Jong S.J. Violation of the energy metabolism of taurine-deficient heart. Amino acids. 2016;48:549-558. D0I:10.1007/s00726-015-2110-2.
Azuma J, Sawamura A, Awata N. Benefits of taurine in chronic congestive heart failure. Jp Circ JP 95-99.
Ahmadian M, Roshan D, Ashurpor E. Taurine supplementation improves functional capacity, myocardial oxygen consumption, and electrical activity in heart failure. Appendix G diet. 2017;14:422-432. D0I: 10.1080/19390211.2016.1267059.