THE LEVEL OF EXPRESSION OF CD3(2GV6) and CD20(L26) MARKERS IN THE CELLS OF URINARY BLADDER POLYPS AND PAPILLOMA TISSUES
Keywords:
bladder, polyp, papilloma, CD3 and CD20 marker, B-cell lymphocytes, humoral, co- receptorAbstract
This article presents data on the expression level of CD3(2GV6) and CD20(L26) markers in bladder polyp and papilloma tissue cells. The CD 3 marker is a surface marker specific for all subpopulations of T lymphocytes. CD 3 is a co-receptor of the T-cell receptor (TCR). Antigen recognition is the main tissue compatibility molecule located on the surface of cells. CD 20 is a protein often expressed on the surface of B-cell lymphocytes. These cells are the main cells of the immune system that protect the body from infections and are on the surface of immature to mature cells of V-cells. Antibody- producing plasma cells are not treated differently. Based on the level of expression of CD 3 and CD 20 markers in bladder polyps and papillomas, the response of the immune system to the cellular or humoral immune system in polyps and papillomas and the differences between them are presented.
References
Volchenko N.N., Frank G.A. A complex of morphological and prognostic factors in breast cancer: A guide for doctors. - M., 2000.
Immunohistochemical methods: a guide. Translation from English. ed. G.A. Frank and P.G. Malkova // M., 2011, - 224 p.
Pozharissky K.M., Leenman E.N. Significance of immunohistochemical methods for determining the nature of treatment and prognosis of tumor diseases Arkh. patol., 2000; (5): 3–11.Schmitt С.A., Love S.W. Apoptosis and therapy. G. Path., 1999; 187: pp.127–37.
Viale G., Regan M.M., Mastropasqua M.G. et al. Predictive value of tumor Ki-67 expression in two randomized trials of adjuvant chemoendocrine therapy for node-negative breast cancer // J. Natl Cancer Inst. 2009. Vol. 100 (3). Р. 207–212.
WHO Classification of Tumors of the Braest. WHO, Lyon, 2012.
Yerushalmi R., Woods R., Ravdin P.M., et al. Ki-67 in breast cancer: prognostic and predictive potential // Lancet Oncol. 2010. Vol. 11 (2). pp. 174–183.
Shodiev O’lmas Mustafoevich, Expression level of anti-apoptotic protein Bcl-2 in bladder papillomas(2022/8/13).Web of Scientist: International Scientific research Journal. № 3(8) pp. 297-305
Shodiev O’lmas Mustafoevich, Khaidarova Nargiza Akhtamovana (2022/6/19) EPITELIAL SAFE TUMORS OF BLADDER RATE, TYPES AND CAUSES. Web of Scientist: International Scientific research Journal. .№ 3(6) pp.905-912
