MICROBIOLOGICAL RECOGNITION OF ANTIBODIES TO ANTIGENS OF MICROORGANISMS IN WOMEN WITH INFLAMMATORY DISEASES OF THE GENITAL
Keywords:
Enzyme immunoassay, women, inflammatory diseases of the genitals, antibodies, antigensAbstract
This article intends to study and determine the diagnostic value of determining the titers of antibodies to antigens of certain etiological agents of inflammatory diseases of the genitalia in women of childbearing age. The Subject and methods are to achieve the goal, 304 women of reproductive age with inflammatory diseases of the genitals were studied.ELISA settings were performed using diagnostic test systems for determining serum antibodies to antigens Chlamydia spp, Toxoplasma gondi, Mycoplasma spp, Cytomegalovirus, herpes simplex vi ruses type 1 and 2 - HSV 1,2 (test systems from XEMA, RF) Ureoplasmaurealyticum (test system of the company "Vector-Best", Russia). Antibodies to Mycoplasma spp were detected in the examined women; they were detected in 115 cases (35.5 ± 3,1%). It turned out that the monoculture of microorganisms is detected 3.2 times more often than associations, in 6,7% of cases negative samples are detected. Most antibodies were detected against antigens of other species Mycoplasma spp, Chlamydia spp, Cytomegalovirus and Herpes simplex virus types 1 and 2. A total of 287 positive samples were found, including 55 monocultures and 232 microorganisms. Women who were examined most often in association met with cytomegalovirus and Chlamydia spp 15 times, Mycoplasma spp 10 times with other microorganisms and with each other.
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