DYNAMICS OF GAS EXCHANGE AND ACID-BASE STATE IN THERAPY OF MDR-TUBERCULOSIS WITH THE INCLUSION OF ANTIOXIDANT SUPPORT
Keywords:
gas exchange, acid-base balance, hypoxia, respiratory failure, antioxidant therapy.Abstract
The effect of thiotriazoline on the restoration of gas exchange parameters and acid-base balance in patients with MDR tuberculosis was studied. It was found that the drug accelerates the normalization of PaO₂, PaCO₂ and pH, reduces the severity of respiratory failure and improves the functional state of the lungs.
References
Maksimov I.B. Antioxidant therapy in the treatment of tuberculosis // Archives of pathology. - 2021. - V. 83, No. 4. - P. 43–48.
Sokolova I.V. Energy metabolism during hypoxia and the role of thiotriazoline // Vestn . biology and medicine. - 2017. - V. 5, No. 3. - P. 122-127.
Kuznetsova MA Thiotriazoline in tuberculosis treatment: clinical experience // Terapevt . Arkhiv . – 2020. – Vol . 92, No. 1. – P. 55–58.
Romanov A.I. Oxidative stress in tuberculosis: mechanisms and significance // Pulmonology. - 2020. - Vol. 30, No. 2. - P. 65–70.
Blinova OV Modern aspekty pathogenetic therapy tuberculosis // Med. science i obrazov . Urala . – 2021. – №3. – P. 15–19.
Arkhipova L.P. Thiotriazoline and cytokine status in patients with tuberculosis // Rus. medical journal. – 2014. – V. 22, No. 5. – P. 29–33.
Shovkun I.Yu., Ivanov V.S., Mishchenko T.M. Hepatoprotective effect of thiotriazoline in tuberculosis // Health of Ukraine. - 2013. - No. 6 (2). - P. 18-21.
