FEATURES OF THE COURSE, MORPHO-FUNCTIONAL AND CLINICAL-INSTRUMENTAL INDICATORS OF COMMUNITY-ACQUIRED PNEUMONIA WITH MYOCARDITIS IN CHILDREN
Keywords:
pneumonia, myocarditis, children, ExoKG, analysis, laboratory, fibrinolysis, prothrombin, hemostasis, bloodAbstract
Myocarditis is an inflammatory lesion of the myocardium of infectious, toxic-infectious, infectious-allergic, autoimmune, or toxic etiology (3,4). Despite the research, the problem of myocarditis in children remains unresolved, which is associated with a variety of etiological factors and clinical, laboratory and instrumental manifestations of the disease. The search for differential diagnostic criteria and additional methods of pathogenetic therapy for the disease continues. In the study, in the majority of children with pneumonia, the plasma component of hemostasis was activated, a shortening of clotting time, hyperfibrinogenemia, a decrease in platelets, prothrombin index, and fibrinogen occurred; in a minority (19.64%) of children with pneumonia, the fibrinolytic activity of the blood increased. The authors recommend correcting the detection of changes with hemostabilizing drugs. The paper presents the results of anamnestic, clinical, generally accepted laboratory and unique examination methods in 80 children with community-acquired pneumonia aged 1 to 6 years, of which 40 patients with concomitant myocarditis who were hospitalized in the departments of the II Emergency Pediatrics and Pediatric Intensive Care Unit of Samarkand branch of the Republican Scientific Center for Emergency Medical Care in the period from 2020 to 2022.
References
Zakirova B. I., Mamarizaev I. K. The course of recurrent respiratory infections in children against the background of atopic dermatitis.
J //Questions of science and education. – 2021. – T. 9. – P. 134.
Leung S. Y. et al. Short-term association among meteorological variation, outdoor air pollution and acute bronchiolitis in children in a subtropical setting //Thorax. – 2021. – Т. 76. – №. 4. – pp. 360-369.
Zakirova B.I. et al. Broncho-obstructive syndrome: prognostic significance of intestinal dysbiosis in its development
// Achievements of science and education. – 2020. – No. 10 (64). – pp. 83-85.
Jat K. R., Dsouza J. M., Mathew J. L. Continuous positive airway pressure (CPAP) for acute bronchiolitis in children //Cochrane database of systematic reviews. – 2022. – №. 4.
Rustamov М. . ., Ibragimova М. ., & Xusainova Ш. . (2023). FEATURES OF CLINICAL AND DIAGNOSTIC CRITERIA OF MYCOPLASMA PNEUMONIA IN CHILDREN. International Journal of Scientific Pediatrics, 2(2), 05–08. https://doi.org/10.56121/2181-2926-2023-2-05-08
Fedorovna, I. M., & Mamedovich, S. N. (2022). Improving Treatment in Children with Community-Acquired Pneumonia with Atypical Etiology. Telematique, 4644-4648
Dafydd C. et al. Efficacy and safety of high flow nasal oxygen for children with bronchiolitis: systematic review and meta-analysis //BMJ Open Respiratory Research. – 2021. – Т. 8. – №. 1. – p. e000844.
Fedorovna, I. M., & Shodiyorovna, G. D. (2023). Improved diagnosis and treatment of atypical pneumonia in children. Thematics Journal of Applied Sciences, 7(1).
Cai Z., Lin Y., Liang J. Efficacy of salbutamol in the treatment of infants with bronchiolitis: A meta-analysis of 13 studies //Medicine. – 2020. – Т. 99. – №. 4.
Kenmoe S. et al. Systematic review and meta-analysis of the prevalence of common respiratory viruses in children< 2 years with bronchiolitis in the pre-COVID-19 pandemic era //PLoS One. – 2020. – Т. 15. – №. 11. – p. e0242302.
Jerkic S. P. et al. Postinfectious bronchiolitis obliterans in children: diagnostic workup and therapeutic options: a workshop report //Canadian Respiratory Journal. – 2020. – Т. 2020.
