MEDICAL MISTAKES IN THE USE OF ANTIBACTERIAL DRUGS OF THE CEPHALOSPORIN GROUP AT THE OUTPATIENT STAGE OF TREATMENT

Abstract

In order to study the structure of medical mistakes made in prescription of antimicrobial drugs of the cephalosporin group (CF) in the treatment of patients with respiratory pathology, data on the use of antimicrobial drugs from 381 outpatient follow-up cards of patients for the period from 2019-2020 were copied.

Analysis of medical documentation showed a high proportion of the use of cephalosporins (60.3%) in primary health care institutions, which is accompanied by several medical errors.

Medical errors associated with the use of an antibiotic of the cephalosporin group, in the absence of indications / or according to an unregistered indication, amount to 57.8%, where they were used, without additional clinical clarifications and examination, in 42.9% of cases in the treatment of patients with asthma, in 50.0% – with ARVI and in 3.6% - with lung sarcoidosis. 26.6% of cases of medical errors are associated with various violations of the dose regime, including non-compliance with the frequency of use of cephalosporins in 6.2%, exceeding their recommended dose in 1.6%, the use of an antibiotic in a low dose in 2.1% and in 7.9% of cases, too long duration of therapy was noted. Medical errors associated with incorrect tactics of antibiotic use account for 15.6%, reflected by the facts of irrational change of antimicrobial therapy regimen with its ineffectiveness in 5.2% of cases, untimely change of antimicrobial drug with its ineffectiveness in 5.7%, incorrect tactics of the treatment regimen in 4.7%.

Strengthening pharmacovigilance measures in the system of antimicrobial use, analysis of medical errors in the use of antimicrobial drugs, registration of all cases of adverse reactions as a result of incorrect use of antimicrobial drugs will increase the effectiveness and safety of drug therapy and thereby improve the quality of medical care and contribute to overcoming antibiotic resistance.