ASPIRATSIYA SINDROMIDAN VAFOT ETGAN CHAQALOQLARDA BUYRAKDAGI MORFOLOGIK O'ZGARISHLAR
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chaqaloq, neonatal davr, buyrak morfologiyasi##article.abstract##
Chaqaloqlarda aspiratsiya sindromi hali ham neonatologiyada dolzarb tadqiqot mavzusi bo'lib qolmoqda, klinik ahamiyatiga qaramay, yangi tug'ilgan chaqaloqlar va chaqaloqlarda tug'ruqdan keyingi aspiratsiyaga unchalik e'tibor berilmagan. 2018-2022 yillarda neonatal davrda respublika patologik anatomiya markazida erta neonatal davrda vafot etgan jami 72 ta yangi tug'ilgan chaqaloq va ularning buyrak to'qimalari materiallari olingan.
7 kungacha bo'lgan davrda aspiratsiya sindromi bo'lgan chaqaloqlarda glomerulyar shakllanishning deformatsiyasi natijasida buyrak gipoksiyasi tufayli glomerulyar tuzilmalardagi mezangial hujayralarning proliferativ faolligi oshishi aniqlandi.
Erta neonatal davrda chaqaloqlarda (0-7 kungacha bo'lgan davr) buyrak homila ichi pnevmoniya bilan boshlangan, aspiratsiya sindromi natijasida 3 kun ichida vafot etgan yangi tug'ilgan chaqaloqlarning buyraklarida segmental nekrotik nefroz o'choqlari paydo bo'lgan.
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