EFFECTIVENESS OF COMPLEX PREVENTION MEASURES FOR VIRAL HEPATITIS B AND C: CLINICAL-EPIDEMIOLOGICAL DYNAMICS AND EDUCATIONAL EFFECT

Abstract

Viral hepatitis B and C continue to be one of the most significant public health problems, determining the high prevalence of chronic liver diseases, cirrhosis, and hepatocellular carcinoma. Despite the implementation of the National Program of the Republic of Uzbekistan (2022-2026), a low level of public awareness, low commitment to preventive measures, and pronounced regional differences in the spread of infection persist. This study includes a comprehensive assessment of 240 respondents, including 200 patients with various forms of viral hepatitis B and C and 40 healthy individuals. Analysis of clinical-epidemiological, immunological, and socio-hygienic characteristics made it possible to identify the main barriers to prevention, identify risk factors, and assess the effectiveness of existing measures - vaccination, screening, and sanitary-educational activities. Based on the data obtained, an improved set of preventive measures has been developed, including expanding testing coverage, increasing vaccination accessibility, optimizing epidemiological surveillance, and improving sanitary literacy. The implementation of the proposed model allows predicting a decrease in morbidity by 18-22% and an increase in vaccination coverage to 85%, which confirms the high practical significance of the study.