ODAM PAPILLOMAVIRUSI BILAN KASALLANGAN BEMORLARDA OG‘IZ BO‘SHLIG‘I SHILLIQ QAVATI KASALLIKLARINING KLINIK XUSUSIYATLARINI BAHOLASH
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odam papillomavirusi, og‘iz bo‘shlig‘i shilliq qavati, klinik shakllar, kechish bosqichlari, stomatit, papillomatoz, residiv, xavf omillari##article.abstract##
Odam papillomavirusi (OPV) infeksiyasi og‘iz bo‘shlig‘i shilliq qavati kasalliklarining shakllanishi, klinik kechishi va residivlanishida asosiy etiopatogen omillardan biri hisoblanadi. Virusning epitelial hujayralarda uzoq muddat saqlanib qolishi mahalliy immun javobning izdan chiqishi, epiteliy differensiatsiyasi buzilishi, regeneratsiya jarayonlarining sekinlashishi va surunkali yallig‘lanishning rivojlanishiga olib keladi. Klinik jihatdan bu holat eroziv-yazrali stomatit, papillomatoz o‘smalar, giperkeratoz, atrofik va displastik o‘zgarishlar, shuningdek uzoq davom etuvchi va takrorlanuvchi kechish bilan namoyon bo‘ladi. Ushbu kengaytirilgan tadqiqotda OPV infeksiyasi bilan kasallangan bemorlarda og‘iz bo‘shlig‘i shilliq qavati kasalliklarining klinik spektri, og‘irlik darajalari, klinik kechish bosqichlari, residiv chastotasi, xavf omillari hamda prognoz ko‘rsatkichlari kompleks ravishda tahlil qilindi. Olingan natijalar stomatologiya amaliyotida erta diagnostika, xavf guruhlarini aniqlash va individual davolash strategiyasini ishlab chiqish uchun ilmiy va amaliy ahamiyatga ega.
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