CLINICAL AND DIAGNOSTIC SIGNIFICANCE OF LOCAL PROTECTIVE FACTORS IN CHRONIC RECURRENT APHTHOUS STOMATITIS

Authors

  • Kamilov Xaydar Pozilovich
  • Usmanova Lazzat Baxodirovna

Keywords:

recurrent aphthous stomatitis, diagnosis, aphthae, oral mucosal diseases, differential diagnosis.

Abstract

Chronic recurrent aphthous stomatitis (CRAS) is one of the most common diseases of the oral mucosa, characterized by the periodic occurrence of painful aphthous ulcers in the absence of systemic infection signs. Despite its high prevalence, the etiology of the disease remains multifactorial and not fully understood. Therefore, timely and accurate diagnosis is an essential prerequisite for effective treatment.

This article discusses modern approaches to the diagnosis of recurrent aphthous stomatitis, including clinical assessment, differential diagnosis, laboratory investigations, as well as evaluation of disease severity and patients’ quality of life.

References

Scully C., Porter S. Og‘iz shilliq qavati kasalliklari: qaytalanuvchi aftoz stomatit.

Preeti L., Magesh K.T., Rajkumar K., Karthik R. Qaytalanuvchi aftoz stomatit.

Ship J.A., Chavez E.M., Doerr P.A., Henson B.S., Sarmadi M. Qaytalanuvchi aftoz stomatit.

Lewkowicz N., Lewkowicz P., Dzitko K. va boshq. Recurrent aftoz stomatitli bemorlarda CD4(+) CD25(high) T-regulyator hujayralarining buzilishi // J. Oral Pathol. Med. – 2008. – Vol. 3.

Kamilov X.P., Rustamova D.M. Vobenzim qo‘llash orqali surunkali retsidivli aftoz stomatitni kompleks davolash samaradorligi // O‘zbekiston tibbiyot jurnali. – Toshkent, 2006.

Kamilov X.P., Shukurova U.A. Surunkali aftoz stomatitning umumiy og‘irlik indeksi bo‘yicha klinik baholash: Uslubiy tavsiyalar. – Toshkent, 2008.

Kamilov X.P., Shukurova U.A. FarGALS preparatlarini surunkali retsidivli aftoz stomatitda kompleks davolashda qo‘llash: Uslubiy tavsiyalar. – Toshkent, 2009.

Berlutti F., Pilloni A., Pietropaoli M., Polimeni A., Valenti P. Lactoferrin and oral diseases: current status and perspective in periodontitis // Ann Stomatol (Roma). - 2011. - Vol. 2, № 3-4. - P. 8-10.

Paesano R., Berlutti F., Pietropaoli M., Pantanella, E., Pacifici W., Goolsbee P., Valenti P. Lactoferrin efficacy versus ferrous sulfate in curing iron deficiency and iron deficiency anemia in pregnant women // Biometals. - 2010. - Vol. 23. - P. 7-41.

Rabinovich O.F., Rabinovich I.M., Panfilova E.L., Vakhrushina E.V. Recurrent aphthous stomatitis – aetiology, pathogenesis (part I) // Stomatologiya. – 2010. - №1. – P. 71-74.

Rustamova D.A., Shukurova U.A. Peculiarities of the clinical course of chronic recurrent aphthous stomatitis in patients with blood disorders // Stomatologiya. – Tashkent, 2008. - № 3-4. – P. 98-100.

Published

2026-04-26