ASSESSMENT OF COGNITIVE IMPAIRMENTS IN YOUNG PATIENTS WITH CHRONIC ALCOHOLISM AND OPTIMIZATION OF THERAPEUTIC APPROACHES
Keywords:
chronic alcoholism, cognitive impairment, young patients, MMSE, MoCA, nootropic therapyAbstract
Chronic alcoholism remains one of the leading medical and social problems, accompanied by the development of cognitive impairments, especially in young individuals. Early diagnosis and timely correction of cognitive deficits are essential for improving prognosis and patients’ social adaptation. Aim of the study was to assess cognitive functions in young patients with chronic alcoholism and to substantiate approaches for optimizing therapy. Materials and methods. Patients of young age diagnosed with chronic alcoholism were examined. Standardized neuropsychological scales (MMSE, MoCA) and methods for assessing psycho-emotional status were used to evaluate cognitive functions. A comparative analysis with a control group was performed. The effectiveness of therapy was assessed dynamically during complex treatment including nootropic drugs. Results. A significant reduction in cognitive functions was found in patients with chronic alcoholism compared to the control group (p < 0.05), mainly due to impairments in memory, attention, and executive functions. A correlation was identified between the duration of alcohol dependence and the severity of cognitive deficits (p < 0.01). Complex therapy with the inclusion of nootropic agents led to a statistically significant improvement in cognitive indicators (p < 0.005) and a reduction in anxiety and depressive symptoms. Conclusion. Chronic alcoholism in young individuals is associated with the development of cognitive impairments. The inclusion of nootropic therapy in complex treatment improves cognitive functions and psycho-emotional status of patients.
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