IMMUNOLOGICAL ASPECTS OF DIAGNOSIS AND TREATMENT OF SICK CHILDREN WITH CHRONIC PURULENT MEDIUM OTITITIS ON THE BACKGROUND OF CHRONIC HEPATITIS
Keywords:
chronic hepatitis, immunogram, cellular and humoral immunity, imunofan, chronic otitis mediaAbstract
The immunograms of 93 sick children with chronic purulent otitis media on the background of chronic hepatitis (39 mesotympanitis and 54 epitympanitis) were studied. A comparative analysis of immunogram indices was carried out depending on the severity of inflammatory changes and the inclusion of imunofan in the therapy regimen. The results of the work showed that in sick children with chronic purulent otitis media against the background of chronic hepatitis, the immunogram reflects the peculiarities of the course of the inflammatory process. Chronic inflammatory process in the temporal bone and surgical trauma sharply suppress cellular and humoral immunity, which prompts the use of immunocorrectors in the scheme of postoperative treatment. The inclusion of imunofan in the therapy scheme allowed to completely normalize the immunogram indices in patients with epitympanitis and to improve the clinical course of the postoperative period.
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