SIDE EFFECTS OF GLUCOCORTICOID THERAPY ON THE GASTROINTESTINAL TRACT IN THE TREATMENT OF PATIENTS WITH GLOMERULONEPHRITIS IN CHILDREN AND THEIR PREVENTION
Keywords:
glomerulonephritis, glucocorticoids, gastritis, ulcerAbstract
This article comprehensively examines and analyzes the gastrointestinal side effects of glucocorticosteroids used to treat patients with glomerulonephritis. The study examined the incidence of gastritis, ulcers, and gastrointestinal bleeding in 120 patients with nephrotic syndrome aged 5-18 years who were treated with glucocorticosteroids. The results showed that the use of gastroprotective agents significantly reduces the incidence of complications.
References
American Journal of Nephrology. Clinical studies on glomerulonephritis. – 2023.
Basic & Clinical Pharmacology / B.G. Katzung. – New York: Mc Graw-Hill, 2021.
Brenner B.M., Rector F.C. The Kidney. – Philadelphia: Elsevier, 2020.
20. Brenner B.M., Rector F.C. The Kidney.- Philadelphia: Elsevier,2020.
George C., Mogueo A., Okpechi I., Echouffo-Tcheugui J.B., Kengne A.P. Chronic kidney disease in low-income to middle-income countries: the case for increased screening. BMJ. Glob. Health. 2017; 2(2): Р.256.
Goodman and Gilman’s The Pharmacological Basis of Therapeutics. – Mc Craw-Hill, 2022.
Go D.S., Kim S.H., Park J., Ryu D.R., Lee H.J., Jo M.W. Cost-utility analysis of the National Health Screening Program for chronic kidney disease in Korea. Nephrology (Carlton). 2019; 24(1): 56–64.
Harrison’s Principles of Internal Medicine. – New York: McGraw-Hill, 2022.
Daminova M.A. Chronic kidney disease in children: etiology, classification and progression factors // Bulletin of modern clinical medicine. - 2016. - V. 9 (2). - P. 36-41.
Davydov V.V., Arekhina E.L. The role of cystatin C in early diagnosis of chronic kidney disease progression in patients with acute decompensation of chronic heart failure//Consiliummеdicum. 2018. - No. 12. - P. 30-34.
Dildabekova A.S. Cystatin C in the diagnosis of acute and chronic kidney injury // International Journal of Applied and Fundamental Research. 2016. No. 11-1. P. 66-70.
Dildabekova A.S., Abeuova B.A., Begaidarova R.Kh. Cystatin C in the diagnosis of glomerular filtration dysfunction in children with acute intestinal infections // Issues of Practical Pediatrics. - 2017. - No. 1. - P. 41-43 .
European Renal Association. Clinical Guidelines. – 2022.
KDIGO Clinical Practice Guideline for Glomerulonephritis. – Kidney International Supplements, 2021.
Koppe L., Fouque D. The Role for Protein Restriction in Addition to Renin Angiotensin-Aldosterone System Inhibitors in the Management of CKD. Am. J. Kidney Dis. 2019;73(2):248–257.
Lancet Gastroenterology & Hepatology. – 2022.
Munter P., He J, Hamm L. et al. Renal insufficiency and subsequent death resulting from cardiovascular disease in the United States //Am.soc Nephrol-2012, 13,745-753.
Sleisenger M.H., Feldman M. Gastrointestinal and Liver Disease. – 2021.
Saran R., Robinson B., Abbott K.C., Agodoa L.Y.C., Bragg-Gresham J., Balkrishnan R., Bhave N., Dietrich X., Ding Z., Eggers P.W., Gaipov A., Gillen D., Gipson D., Gu H., et al. US Renal Data System 2018 Annual Data Report: Epidemiology of Kidney Disease in the United States. Am. J. Kidney Dis. 2019; 73(3S1):A7–A8.
Smirnova N.N.Modern biomarkers of kidney injury in pediatrics // Nephrology. - 23(4).-2019.-С. 112-118. https://doi.org/10.24884/1561-6274-2019-23-4-112-118
Tantisattamo E., Dafoe D.C., Reddy U.G., Ichii H., Rhee C.M., Streja E., Landman J., Kalantar-Zadeh K. Current Management of Acquired Solitary Kidney. Kidney International Reports. 2019; 4(9):1205–1218.
Textbook of Gastroenterology. – Wiley-Blackwell, 2021.
Talley N.J., Ford A.C. Gastroenterology. – London: Elsevier, 2020.
World Journal of Gastroenterology. Steroid-induced гастропатия. – 2022.
