FEATURES OF THE FORMATION OF GASTROINTESTINAL TRACT DISEASES IN CHILDREN UNDER CONDITIONS OF METABOLIC AND NUTRITIONAL DISORDERS

Authors

  • Ataeva Mukhiba Saifievna
  • Kayumova Shahlo Shukhratovna

Keywords:

children, gastroenterological pathology, abdominal pain, gastrointestinal diseases, outpatient stage, functional disorders

Abstract

Diseases of the digestive organs in children remain one of the most common reasons for seeking medical attention at the outpatient level and are characterized by a tendency towards growth, polymorphism of clinical manifestations, and a high frequency of chronicity. The problem is of particular importance in primary healthcare, where early differentiation of functional and organic pathologies of the gastrointestinal tract is required.Purpose of the research. Study the structure of gastroenterological pathology and the features of the clinical course of digestive system diseases in children observed in outpatient settings.Materials and methods. A clinical observation study was conducted on 68 children with gastroenterological pathology examined at the 13th City Family Polyclinic in Samarkand. Patients' complaints, anamnestic data, clinical syndromes, and the nosological structure of the diseases were assessed. A comparative analysis of clinical manifestations in functional and organic diseases of the gastrointestinal tract was conducted using statistical processing methods.Results. It was established that functional disorders predominated in the structure of gastroenterological pathology (58.8%), while a significant proportion of organic diseases remained (41.2%).

References

Choglee A., Velasco-Benitez C., Coppen I., et al. Multicultural aspects of functional gastrointestinal disorders in children // J. Pediatr. Gastroenterol. Nutr. - 2021. - Vol. 72, No. 3. - P. 360-368.

Drossmann D.A., Hasler V.L. Rome IV - functional disorders of the gastrointestinal tract: disorders of intestinal-cerebral interaction // Gastroenterology. - 2020. - Vol. 158, No. 6. - P. 1528-1539.

Guarino A., Ashkenazi S., Gendrel D., et al. European Society for Pediatric Gastroenterology guidelines for acute gastroenteritis // J. Pediatr. Gastroenterol. Nutr. - 2021. - Vol. 72, No. 2. - P. 284-301.

Hojak I., Fabiano V., Pop T.L. et al. Guide to the use of probiotics in pediatric gastroenterology // J. Pediatr. Gastroenterol. Nutr. - 2020. - Vol. 71, No. 1. - P. 130-147.

Homan M., Orel R. Are functional gastrointestinal disorders truly functional? // World J. Gastroenterol. - 2020. - Vol. 26, No. 21. - P. 2674-2684.

Hyams J.S., Di Lorenzo C., Sapiens M., et al. Functional disorders of the gastrointestinal tract: children and adolescents // Gast.

Indrio F., Martini S., Francavilla R., et al. Intestinal-cerebral axis in children // Front. Pediatrician. - 2021. - Vol. 9. - Article ID 634280.

Koppen I.J.N., Nurko S., Saps M. et al. Children's Rome IV criterion: what's new? // Expert Rev. Gastroenterol. Hepatol. - 2020. - Vol. 14, No. 3. - P. 193-201.

Koppen I.J.N., Vriesman M.H., Saps M. et al. Functional disorders of defecation in children // Lancelet Gastroenterol. Hepatol. - 2022. - Vol. 7, No. - P. 159-174.

Korterink J.J., Ockeloen L., Hilbink M. et al. Children's Gastrointestinal Functional Disorders: A Systematic Review // World J. Gastroenterol. - 2020. - Vol. 26, No. 31. - P. 4599-4613.

Lewis M.L., Palsson O.S., Whitehead W.E. Increasing the use of medical care in children with functional disorders of the gastrointestinal tract // J. Pediatr. - 2021. - Vol. 231. - P. 172-178.

Mahajan L., Willie R. Chronic abdominal pain in children // Kline. Pediatrician. - 2021. - Vol. 60, No. 1. - P. 8-16.

Martin A.E., Newlaw-Delgado T.V., Abbot R.A. et al. Epidemiology of Functional Disorders of the Gastrointestinal Tract in Children // Pediatrics. - 2022. - Vol. 149, No. 1. - p.2021054104.

Robin S.G., Keller K., Zwiner R., et al. The prevalence of functional diseases of the gastrointestinal tract in children using the criteria of Rome IV // Gastroenterology. - 2021. - Vol. 161, No. 1. - P. 99-110.

Rosen R., Vandenplas Y., Singendonk M. et al. Guide to the clinical practice of pediatric gastroesophageal reflux // J. Pediatr. Gastroenterol. Nutr. - 2021. - Vol. 72, No. 1. - P. 1-23.

Saps M., Bonilla S. Early life events: infants and children with functional gastrointestinal disorders // J. Pediatr. Gastroenterol. Nutr. - 2020. - Vol. 70, No. 4. - P. 523-530.

Saps M., Nichols-Vinueza D.X., Rosen J.M., Velasco-Benitez C.A. Prevalence of abdominal pain disorders in children worldwide // Am. J. Gastroenterol. - 2022. - Vol. 117, No. - P. 262-270.

Saps M., Velasco-Benitez C.A., Langshaw A.H., Ramírez-Hernández C.R. Prevalence of functional gastrointestinal disorders in children and adolescents: a meta-analysis // J. Pediatr. - 2021. - Vol. 228. - P. 107-114.

Scarpato E., Kolachek S., Yozhkitz-Pavkov D. et al. Children's Gastrointestinal Functional Disorders: Update // Acta Paediatr. - 2020. - Vol. 109, No. 6. - P. 1184-1192.

Størdal K., Nygaard E.A., Bentsen B.S. Organic versus functional gastrointestinal disorders in children // Arch. Dis. Child. - 2020. - Vol. 105, No. 6. - P. 551-556.

Szajewska H., Horvath A. Functional abdominal pain disorders in children: current evidence // Curr. Opin. Pediatrician. - 2021. - Vol. No. 33, No. 5. - P. 588-595.

Tabbers M.M., DiLorenzo C., Berger M.Yu. et al. Assessment and treatment of functional constipation in infants and children: ESPGHAN/NASPGHAN recommendations // J. Pediatr. Gastroenterol. Nutr. - 2021. - Vol. 73, No. 2. - P. 221-246.

Thapar N., Benninga M.A. Pediatric functional bowel disorders // Lancet Child Adolesc. health - 2023. - Vol. 7, No. 4. - P. 280-292.

Thapar N., Benninga M.A., Crowell M.D. et al. Pediatric functional abdominal pain disorders // Nat. Rev. Dis. Primers. - 2020. - Vol. 6. - A.

van Tilburg M.A.L., Hyman P.E., Walker L. et al. The prevalence of functional gastrointestinal disorders in children and adolescents // Klin. Gastroenterol. Hepatol. - 2021. - Vol. 19, No. 2. - P. 357-364.

Vandenplas J., Abkari A., Bellayche M. et al. Children's Gastroesophageal Reflux Disease: Practical Kazhevskaya H., Khorvat A. Functional Abdominal Pain Disorders in Children: Current Evidence // Curr. Opin. Pediatrician. - 2021. - Vol. No. 33, No. 5. - P. 588-595.

Vasant D.H., Payne P.A., Black C.J. British Society of Gastroenterology Guide to Intestinal-Cerebral Interaction Disorders // Gut. - 2021. - Vol. 70, No. 7. - P. 1214-1240.

Zeevenhooven J., Browne P.D., L'Hoir M.P., Benninga M.A. Infant colic: mechanisms and management // Nat. Rev. Gastroenterol. Hepatol. - 2020. - Vol. 17, No. 8. - P. 479-496.

Zeevenhooven J., Koppen I.J.N., Benninga M.A. The new Rome IV criteria for functional gastrointestinal disorders in infants and toddlers // Pediatr. Gastroenterol. Hepatol. Nutr. - 2020. - Vol. 23, No. 1. - P. 1-13.

Shabalov N.P. Children's Gastroenterology. - 6th ed., revised and expanded. - M.: MEDpress-inform, 2023. - 640 p.

Published

2026-05-16