BO`LMACHALAR FIBRILATSIYASI BILAN ASORATLANGAN ARTERIAL GIPERTENZIYA BILAN OG'RIGAN BEMORLARDA YURAK-QON TOMIRLARINI QAYTA QURISH XUSUSIYATLARI
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bulmacha fibrilatsiyasi, arterial gipertenziya, indekslangan chap bulmacha hajmi, chap qorincha gipertrofiyasi, intima-media kompleksi qalinligi, mikroalbuminuriya##article.abstract##
Bo’lmachalar fibrillatsiya (BF) yurak ritmining eng keng tarqalgan jiddiy buzilishi va ishemik insultning keng tarqalgan sababidir. Arterial gipertenziya (AG) BF rivojlanishiga olib keladigan xavf omillaridan biri ekanligi ma'lum. Chap qorincha va chap bo’lmacha miokardini qayta qurish gipertoniya bilan og'rigan bemorning yuragidagi elektrofiziologik o'zgarishlarga asoslanadi, bu yurak aritmiyalarini, shu jumladan BF ni qo'zg'atishga olib keladi. Gender farqlarining ta'sirini, xususan, testosteron darajasining AF va ishemik insultni rivojlanish xavfiga ta'sirini isbotlovchi tadqiqotlar mavjud.
Tadqiqot maqsadi: gender farqlarini hisobga olgan holda, bo’lmachalar fibrilatsiya bilan asoratlangan arterial gipertenziya bilan og'rigan bemorlarda yurak-qon tomir tizimini qayta qurish xususiyatlarini aniqlashdir.
Materiallar va tadqiqot usullari. Biz har ikkala jinsdagi AG (erkaklar n = 60, ayollar n = 74) bo'lgan 134 nafar bemorni tekshirdik, ularda dastlab paroksismal shakl n = 12 (8,9%), doimiy shakl n = 43 (32,1%) va doimiy shakl BF n=79 (59%) tashxisi qo'yilgan.Tadqiqot boshida BF bilan og'rigan AG bemorlarining o'rtacha yoshi 65,49 ± 11,3 yil edi. Dastlab, shifokor ko’rigi vaqtidagi qon bosimi Korotkov usuli bilan o'lchandi, exokardiografik tadqiqot o'tkazildi. Strukturaviy qon tomir o'zgarishlar darajasi umumiy uyqu arteriyasining intima / media kompleksi (IMK) qalinligi bilan aniqlangan, ertalab siydikda dupleks skanerlash va mikroalbuminuriya (MAU) bilan baholangan.
Xulosa: Tadqiqot natijasida AG bilan og'rigan ayollarda TMI ortishi va semirishning AG rivojlanish xavfi bilan bog'liqligi qayd etildi. AG va BF bo'lgan ayollar guruhida MAU darajasi erkaklarnikiga qaraganda sezilarli darajada yuqori bo'lib, me'yoriy qiymatlardan oshib ketgan, bu qon tomir buzilishlarning og'irligini ko'rsatadi. Doimiy BF bo'lgan erkaklarda, doimiy va paroksismal BF bilan og'rigan bemorlardan farqli o'laroq, chap qorincha va chap bulmachaning kengayishi kattaroq bo'lgan. Holbuki, BF ning doimiy shakli bo'lgan ayollarda, doimiy va paroksismaldan farqli o'laroq, tizimli qon tomir buzilishlarining og'irligi qayd etilgan.
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