QANDLI DIABET 2 TIPI BILAN BIRGALIKDA ARTERIAL GIPERTENZIYA BO’LGAN BEMORLARDA AMPLODIPINNING SAMARADORLIGI
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Arterial gipertenziya, amlodipin, qandli diabet 2-tip##article.abstract##
Gipertoniya kasalligi va qandli diabetning birga kechishi yurak qon-tomir kasalliklari, buyrak yetishmovchiligi xavfini 2-3 barobar oshiradi. Shuning uchun arterial gipertenziyani ham, qandli diabetni ham erta aniqlash va tashxislash, o'z vaqtida tegishli davo muolajalarini belgilash yurak qon-tomir kasalliklar asoratlari rivojlanishini to'xtatishda juda muhimdir. Ion darajasidagi insulin kaltsiy va natriyning hujayraga kirishiga ta'sir qiladi, bu qon tomir silliq mushak tolalarining zo’riqib ishlashiga sabab bo’ladi. Insulinga sezgirlikning pasayishi natijasida hujayraga kaltsiy oqimi kuchayadi va silliq mushak hujayralarining zo’riqishi kuchayadi. Bunday bemorlarda koronar arteriyalarning fiziologik javob reaksiyasi kamayadi (kengayish qobiliyatining pasayishi), bu esa mikrosirkulyatsiyaning buzilishiga olib keladi.
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