KEKSA VA QARIYALARDA SUYUQLIK ISTE’MOLINING O‘LIM KO‘RSATKICHI VA JISMONIY FAOLIYAT DARAJASIGA TA’SIRI
##article.subject##:
suvsizlanish, keksalik, o‘lim, suyuqlik iste’moli, ushlash kuchi##article.abstract##
Kirish: Yetarli miqdorda suyuqlik ichmaslik natijasida kelib chiqadigan suvsizlanish keksa yoshdagi odamlar orasida keng tarqalgan muammo hisoblanadi, biroq uning keksa yoshdagi odamlarda geriatrik holat va o‘limga ta’siri yetarlicha o‘rganilmagan mavzu hisoblanadi.
Vazifasi: iste’mol qilingan suyuqlik miqdorining keksa yoshdagi odamlarda geriatrik holat va o‘limga ta’sirini o‘rganish.
Materiallar va usullar: 68 va undan katta yoshdagi tasodifiy tayinlangan subyektlarning kristall prospektiv kogort tadqiqoti (n=379). Suyuqlik iste’moli Mini nutritiv baholash shkalasi yordamida baholandi. Barcha ishtirokchilar uchun kompleks geriatrik tekshiruv o‘tkazildi. Umumiy kuzatuv davri 6-yilni tashkil etdi.
Natijalar: Kuniga 5 stakandan ko‘proq ichgan ishtirokchilarda kuniga 5 yoki undan kamroq stakan suyuqlik ichganlarga nisbatan jismoniy faoliyat darajasi sezilarli darajada yuqori bo‘lgan. Suyuqlik iste’molining ko‘payishi (kuniga 3 stakandan kamroq 3-5 stakangacha va keyinchalik kuniga 5 stakandan ko‘proq) SPPB ballarini o‘rtacha 1,8 ballga [β (95% CI) = 1,807 (0,697 - 2,918) ] va ushlash kuchini 2,4 kg ga [β (95% CI) 2,440 (0,152 - 4,728) ] oshirdi. Shuningdek, kuniga 5 stakan suyuqlik ichish 6-yillik kuzatuv davomida barcha sabablarga ko‘ra o‘lim xavfining 71% ga pasayishi bilan bog‘liq [OR (95% CI) = 0,29 (0,14 - 0,63) ]. Ushbu bog‘liqlik jins, yosh, kamqonlik, yuqori SRO, depressiya, kognitiv pasayish va insult tarixiga moslashgandan so‘ng statistik ahamiyatga ega bo‘lib qoldi, ammo ovqatlanish holati, jismoniy funksiya va avtonomiyani yo‘qotishga moslashgandan so‘ng yo‘qoldi.
Библиографические ссылки
Aslan Kirazoglu D, Heybeli C, Atcıyurt K, Yigitalp V, Smith L, Veronese N, Rahmati M, Soysal P. The relationship between dehydration and etiologic subtypes of major neurocognitive disorder in older patients // Eur Geriatr Med. - 2024. - Aug;15(4). – С. 1159-1168. doi: 10.1007/s41999-024-00986-z.
Beck AM, et al. Narrative Review of Low-Intake Dehydration in Older Adults// Nutrients. - 2021. - Sep 9;13(9). – С. 3142. doi: 10.3390/nu13093142.
Chan J, Knutsen SF, Blix GG, Lee JW, Fraser GE. Water, other fluids, and fatal coronary heart disease: the Adventist Health Study // Am J Epidemiol. - 2002. - May 1;155(9). – С. 827-833. doi: 10.1093/aje/155.9.827.
Enhörning S, Brunkwall L, Tasevska I, Ericson U, Persson Tholin J, Persson M, Lemetais G, Vanhaecke T, Dolci A, Perrier ET, Melander O. Water Supplementation Reduces Copeptin and Plasma Glucose in Adults With High Copeptin: The H2O Metabolism Pilot Study // J Clin Endocrinol Metab. - 2019. - Jun 1;104(6). – С. 1917-1925. doi: 10.1210/jc.2018-02195.
George Liamis et al. Electrolyte disorders in community subjects: prevalence and risk factors // Am J Med. - 2013. - Mar;126(3). – С. 256-263. doi: 10.1016/j.amjmed.2012.06.037.
Jang H, Sharma AB, Dan U, Wong JH, Knight ZA, Garrison JL. Dysregulation of the fluid homeostasis system by aging // bioRxiv. - 2024. - Sep 27 doi: 10.1101/2024.09.26.615271.
Katamadze NN, Pigarova EA, Dzeranova LK, Mokrysheva NG. Features of water-electrolyte balance in persons of the older age group // Review Probl Endokrinol- 2024 - Jan 24;69(6). – С. 28-36. doi: 10.14341/probl13214.
Kim H, Beom SH, Kim TH, Kim BJ. Association of Water Intake with Hand Grip Strength in Community-Dwelling Older Adults // Nutrients. -2021. - May 21;13(6). – С. 1756. doi: 10.3390/nu13061756.
Lorenzo I, Serra-Prat M, Yébenes JC. The Role of Water Homeostasis in Muscle Function and Frailty: A Review // Nutrients. - 2019. - Aug 9;11(8). – С. 1857. doi: 10.3390/nu11081857.
Nakamura Y, Watanabe H, Tanaka A, Yasui M, Nishihira J, Murayama N. Effect of Increased Daily Water Intake and Hydration on Health in Japanese Adults // Nutrients. - 2020. - Apr 23;12(4). – С. 1191. doi: 10.3390/nu12041191.
Nose H, Morimoto T, Ogura K. Distribution of water losses among fluid compartments of tissues under thermal dehydration in the rat // J Physiol Soc Jpn. - 1983 - 33(6). – С. 1019-1029. doi: 10.2170/jjphysiol.33.1019.
Paik IY, Jeong MH, Jin HE, Kim YI, Suh AR, Cho SY, Roh HT, Jin CH, Suh SH. Fluid replacement following dehydration reduces oxidative stress during recovery // Biochem Biophys Res Commun. - 2009. - May 22;383(1). – С. 103-107. doi: 10.1016/j.bbrc.2009.03.135.
Serra-Prat M, Lorenzo I, Martínez J, Palomera E, Pleguezuelos E, Ferrer P. Relationship between Hydration Status and Muscle Catabolism in the Aged Population: A Cross-Sectional Study // Nutrients. - 2023. - Nov 8;15(22). – С. 4718. doi: 10.3390/nu15224718.
Shiose K, Takahashi H, Yamada Y. Muscle Glycogen Assessment and Relationship with Body Hydration Status: A Narrative Review // Nutrients. - 2022. - Dec 29;15(1). – С. 155. doi: 10.3390/nu15010155.
Turusheva A, Frolova E, Degryse JM. Age-related normative values for handgrip strength and grip strength's usefulness as a predictor of mortality and both cognitive and physical decline in older adults in northwest Russia // Age Ageing. - 2017. - Mar 1;17(1). – С. 417-432.
Turusheva, A., et al., Predictors of short-term mortality, cognitive and physical decline in older adults in northwest Russia: a population-based prospective cohort study // Gerontology.– 2017. – Aug;29(4). – С. 665-673. doi: 10.1007/s40520-016-0613-7.
Zhou HL, Wei MH, Cui Y, Di DS, Song WJ, Zhang RY, Liu JA, Wang Q. Association Between Water Intake and Mortality Risk-Evidence From a National Prospective Study // Front Nutr. - 2022. - Apr 12;9. – С. 822119. doi: 10.3389/fnut.2022.822119.
