BOLALARDA YASHIRIN SILNING MAHALLIY SHAKLLARIGA O‘TISHINING ZAMONAVIY EPIDEMIOLOGIK XAVF OMILLARI
##article.subject##:
latent sil infeksiyasi, zamonaviy epidemiologik xavf omillari, mahalliy sil, bolalar, sil infeksiyasi o‘chog‘i##article.abstract##
Tadqiqotning maqsadi. Umumiy davolash tarmog‘i sharoitida aniqlashni, shuningdek, silga qarshi dispanser sharoitida kuzatishni yanada optimallashtirish maqsadida sil infeksiyasi o‘choqlarida yashovchi bolalarda yashirin sil infeksiyasini silning mahalliy shakllariga o‘tkazishning zamonaviy epidemiologik xavf omillarini tahlil qilish. Materialы i metodы. Sil infeksiyasi o‘choqlarida yashagan LTI bilan kasallangan 62 nafar bola tanlab olindi. Ushbu bolalar LTI bo‘yicha profilaktik kimyoterapiya tugaganidan 12 va 24 oy o‘tgach qayta tekshiruvdan o‘tkazildi. Bolalar ikki guruhga ajratildi. 1-guruhga faol silga o‘tgan latent sil infeksiyasi bilan kasallangan 33 nafar bola kiritilgan; 2-guruhni LTIning faol silga o‘tishi kuzatilmagan 27 nafar bola tashkil etdi. Natijalar. Covid-19 o‘chog‘ida yashash: onasi kasal (RR 3.250), otasi kasal (RR 8,000), OIV infeksiyasi o‘chog‘i: otasi kasal (RR 8,000) kabi omillarning modifikatsiyalovchi roli aniqlandi. Sil infeksiyasining hududiy o‘chog‘i: maktab (RR 4,500), "sobiq" sil o‘chog‘i (RR 8,000) kabi omilning ahamiyati aniqlandi. Xulosalar. Bugungi kunda Covid-19 o‘chog‘ida, OIV infeksiyasi o‘chog‘ida, silning hududiy o‘choqlarida (maktab, silning "sobiq o‘chog‘i") yashashni sil infeksiyasi o‘choqlaridan bolalar o‘rtasida silning lokal shakllariga LTI amalga oshirilishining zamonaviy epidemiologik xavf omillari sifatida ko‘rib chiqish zarur.
Библиографические ссылки
Adzhablayeva D.N. Main epidemiological indicators of respiratory tuberculosis among children and adolescents in the Samarkand region: the state of the problem and possible ways to resolve it // Universum: medicine and pharmacology. – 2014. – № 9(10). – P. 2. (In Russ).
Aksenova V.A., Baryshnikova L.A., Klevno N.I., Kudlay D.A. Screening of children and adolescents for tuberculosis infection in Russia – past, present, future // Tuberculosis and Lung Diseases. – 2019. – Vol. 97, № 9. – P. 59–67. (In Russ).
Anisimova T.P., Adzhablayeva D.N., Kadyrov I.K., Khodzhaeva S.A., Kim A.A. Analysis of cases of complicated course of tuberculous spondylitis // Academic Journal of Western Siberia. – 2013. – Vol. 9, № 1. – P. 46–47. (In Russ).
Federal clinical guidelines for the diagnosis and treatment of latent tuberculosis infection in children. – Moscow: ROOI “Human Health”, 2015. – 36 p.
World Health Organization. Global tuberculosis report 2023. – URL: https://www.who.int/publications/i/item/978924008385eng (accessed: [sana qo‘shiladi]).
Goletti D. et al. Update on tuberculosis biomarkers: from correlates of risk, to correlates of active disease and of cure from disease // Respirology. – 2018. – Vol. 23, № 5. – P. 455–466.
Khodzhaeva S., Adzhablayeva D., Mamatova N. Current issues of genital tuberculosis in women and men. The influence of the tuberculosis process on fertility // Journal of the Doctor's Bulletin. – 2011. – Vol. 1, № 2. – P. 151–153. (In Russ).
Latorre I., Domínguez J. Dormancy antigens as biomarkers of latent tuberculosis infection // Biomedicine. – 2015. – Vol. 2, № 8. – P. 790–791.
Ovsyankina E.S., et al. Risk factors for the development of tuberculosis in children with and without contact with a patient with tuberculosis // Tuberculosis and Lung Diseases. – 2014. – № 10. – P. 20–23.
Plekhanova M.A., Aksenova V.A., Krivtsova L.A. Personalized early diagnosis and prediction of the course of tuberculosis infection in children with the identification of predictors of latent tuberculosis infection and tuberculosis // Tuberculosis and Lung Diseases. – 2021. – Vol. 99, № 1. – P. 33–39. – DOI: http://doi.org/10.21292/2075-1230-2021-99-1-33-39. (In Russ).
