SHIFOXONADAN TASHQARI KORONAVIRUSLI PNEVMONIYADAN KEYIN BEMORLARDA MARKAZIY GEMODINAMIKANI VA TASHQI NAFAS OLISHNI BAHOLASH NATIJALARI
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Shifoxonadan tashqari pnevmoniya, markaziy gemodinamika, tashqi nafas, COVID-19, SARS-CoV-2, hujayra shikastlanishi, hujayra membranasining yorilishi, ishemiya, yallig'lanish sitokinlari, chandiq va perikardit##article.abstract##
SARS-CoV-2 infektsiyasi butun dunyo bo'ylab tinimsiz tarqalishda davom etmoqda va bu COVID-19 epidemiyasini keltirib chiqarmoqda. Bu so'nggi bir necha asrlardagi eng muhim pandemiya bo'ldi; 130 milliondan ortiq odam zarar ko'rgan va global sog'liqni saqlash tizimlari o'z chegaralarigacha cho'zilgan. Ba'zi mualliflar surunkali dikondisirlangan antikor reaktsiyasi, yallig'lanish va immunologik reaktsiyalar, shikastlanishdan keyingi stress yoki hatto SARS-CoV-2 virusi bilan qaytalanish va / yoki qayta infektsiya sabab bo'lishi mumkin, deb taxmin qilishdi. Bu holatlar miyokardning shikastlanishi va yallig'lanish xavfini oshirishi mumkin, bu esa keyinchalik yurakning chap qorincha disfunktsiyasiga olib kelishi mumkin. SARS-CoV-2 infektsiyasi butun dunyo bo'ylab tinimsiz tarqalishda davom etmoqda va bu COVID-19 epidemiyasini keltirib chiqarmoqda. Bu so'nggi bir necha asrlardagi eng muhim pandemiya bo'ldi; 130 milliondan ortiq odam zarar ko'rgan va global sog'liqni saqlash tizimlari o'z chegaralarigacha cho'zilgan. Ushbu alomatlar virusli infektsiyaning o'tkir bosqichi o'tgandan keyin bir necha hafta davom etadi. Greenhalgh va boshqalar, agar alomatlar kasallik boshlanganidan keyin 3-12 hafta davom etsa, bu holatni o'tkir COVID-19, agar alomatlar 3 oydan ortiq davom etsa, uzoq muddatli COVID-19 deb tasnifladi. Ushbu ta'riflar ular o'tkazgan tadqiqotlar natijasida olingan. Ushbu kasallikning tarqalishi to'g'risidagi ma'lumotlar tadqiqotdan tadqiqotga, barcha holatlarning o'ndan ellik foizigacha farq qiladi. Uzoq muddatli COVID-19 sindromi boshqa og'ir infektsiyalardan keyingi o'tkir post-o'tkir sindromlarga nisbatan noyobdir, chunki u hatto engil va o'rtacha darajadagi infektsiyalari bo'lgan va intensiv terapiya bo'limiga yotqizishni talab qilmaydigan bemorlarda ham tasvirlangan. Bu boshqa og'ir infektsiyalardan keyin rivojlanadigan boshqa post-o'tkir sindromlardan farq qiladi. O'tkir COVID-19 dan keyin rivojlanish uchun javobgar bo'lgan jarayonlar haqida to'liq tushunchaga ega emasmiz.
O'tkir COVID-19 ni davolash ko'plab asoratlar bilan bog'liq, chunki aniq tavsiyalar mavjud emas. Bizning ma'lumotimizga ko'ra, hozirgi vaqtda o'tkir COVID-19 bilan og'rigan bemorlarni, xususan, transtorasik ekokardiyografi (TTE) bilan baholangan yurak-qon tomir (YuQT) kasalliklarini har tomonlama baholagan, doimiy o'zgarishlar qay darajada sabab bo'lishi mumkinligini aniqlash uchun oz sonli tadqiqotlar mavjud. simptomlarning davom etishi uchun. Bundan tashqari, o'tkir COVID-19 dan tuzalib ketgan bemorlarning funktsional holatini baholash uchun shkalalarni ishlab chiqishga bir nechta urinishlar qilingan; ammo, bu bemorlarning keyingi parvarishi hali ham munozarali masala.
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