CLINICAL IMMUNOLOGICAL CHARACTERISTICS OF NON-SPECIFIC ULCERATIVE COLITIS
Keywords:
large intestine, lymphocytes, immunology, inflammationAbstract
Non-specific ulcerative colitis (NUC) is one of the most serious and unresolved problems of gastroenterology. NUC is a very common chronic disease of the colon, accompanied by ulcerative-constructive changes in its mucosa. In the world, there are 50-230 cases per 110,000 population. The disease can worsen at absolutely any age, but men and women aged 18-45 are especially susceptible. In smokers, colitis occurs as much as 2 times less often than those who do not smoke.
The occurrence of this disease is influenced by many different factors, the most common among them: infectious, immunological, genetic, and, of course, environmental factors mature working age. In recent years, the state of the immune system, which largely determines the outcome of the disease, has become increasingly important in the pathogenesis of UC.
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