TREATMENT OF COMORBID PATHOLOGY IN PATIENTS WITH RHEUMATOID ARTHRITIS
Keywords:
comorbid pathology, rheumatoid arthritis, cardiovascular diseases, complications, autoimmune thyroiditisAbstract
Autoimmune thyroiditis is one of the most common pathologies of the thyroid gland in rheumatic diseases, in particular rheumatoid arthritis. As a result, autoimmune thyroiditis, leading to hypothyroidism, influences the activity of high clinical and laboratory parameters in RA. Autoimmune thyroiditis is reported to be three times more common in rheumatoid arthritis than in the general population. Combined pathology is a widespread phenomenon that increases in importance with the age of the patient. It is known that comorbidity increases from 10% in patients under the age of 19 to 80% in people 80 years and older. Pathology of the endocrine system is one of the comorbid conditions that are widely found in patients with diseases of the cardiovascular system. It is well known that thyroid hormones have positive inotropic and chronotropic effects on the heart, thereby contributing to a decrease in myocardial oxygen consumption
References
Immunologicheskiye i morfologicheskiye prediktori klinicheskoy geterogennosti patsiyentov s boleznyu Greyvsa (po rezultatam issledovaniya operativnogo materiala щitovidnoy jelezi) / T.V. Saprina, T.S. Proxorenko, N.V. Ryazanseva, I.N. Vorojsova, S.Yu. Martinova, A.N. Dzyuman, A.P. Zima, O.S. Popov, I.A. Xlusov, K.T. Kasoyan, I.P. Shabalova // Byulleten sibirskoy meditsini. 2015. T. 14. № 1. S.81-91. 12.Kazakov S.P.
Rimar O.D., Mustafina S.V., Simonova G.I. Epidemiologicheskiye issledovaniya yodnogo defitsita i tireoidnoy patologii v krupnom sentre Zapadnoy Sibiri 1995–2010 gg. (na primere g. Novosibirska) // Klinicheskaya i eksperimentalnaya tireoidologiya. 2012. T. 8. № 2. S. 50–54.
Polimorfizm S(-1)T gena CD40, svyaz s semeynimi sluchayami autoimmunnix zabolevaniy щitovidnoy jelezi / A.K. Pyankova, V.N. Maksimov, O.D. Rimar, S.V. Mustafina // Klinicheskaya i eksperimentalnaya tireoidologiya. 2013. T. 9. № 3. S. 45–50.
A.S. Avdeyeva, E.N. Aleksandrova, A.A. Novikov, A.V. Smirnov, M.V. Cherkasova, E.L. Nasonov Destruksiya kostnoy tkani pri revmatoidnom artrite: rol autoantitel//Priloj.k jurn. Nauch-praktich revmatol 2013; 51(3): 267–271
A.E. Dvorovkin , V.I. Odin , O.V. Inamova , V.V. Tirenko , M.M. Toporkov, E.N. Sigan. //Priloj.k jurn. Immunologicheskiye i klinicheskiye vzaimosvyazi pri revmatoidnom artrite, assotsiirovannom s autoimmunnim tireoiditom. Geni & kletki Tom XI, № 3, 2016.
N.S. Podchernyayeva, E.I. Bokareva, A.V. Vitebskaya. //Priloj.k jurn. Autoimmunnaya patologiya щitovidnoy jelezi u bolnix yuvenilnoy sklerodermiyey. Kollektiv avtorov, 2015.
Kondratyeva L.V., Popkova T.V. Autoimmunniye zabolevaniya i disfunksiya щitovidnoy jelezi pri revmatoidnom artrite. //Priloj.k jurn. Nauchno-prakticheskaya revmatologiya. 2017;55(2):211–217
F.V. Valeyeva, T.A. Kiseleva, G.R. Axunova. Problemi vzaimosvyazi patologii щitovidnoy jelezi i revmatologicheskix zabolevaniy//Priloj.k jurn. Sibirskiy meditsinskiy jurnal, 2011, Tom 26, № 4, Vipusk 2
Таирова З. К., Шодикулова Г. З., Шоназарова Н. Х. REVMATOID ARTRIT BILAN KASALLANGAN BEMORLARDA KOMORBID KASALLIKLARNING UCHRASH CHASTOTASI //Журнал кардиореспираторных исследований. – 2022. – Т. 3. – №. 4.
Dusmurodovna K. J., Gadaevich G. A., Ismatullaevich T. R. CLINICAL SIGNIFICANCE OF ANEMIC SYNDROME IN PATIENTS WITH CHRONIC HEART FAILURE //Archive of Conferences. – 2020. – Т. 9. – №. 1. – С. 178-186.
Gadaev A. G., Turakulov R. I., Kurbonov A. K. Occurrence of anemia in chronic heart failure and its negative impact on the course of the disease //Medical Journal of Uzbekistan.-2019-2.-S. – 2019. – С. 74-77.
Zikiryayevna S. G., Xudoyberdiyevna S. N., Mamadiyarovich S. A. Pathology of the Thyroid Gland in Women Rheumatoid Arthritis //Texas Journal of Medical Science. – 2022. – Т. 15. – С. 73-77.
Negmatovna, T. E., Khudayberdievich, Z. S., Sayfutdinovich, K. Z., Khidirnazarovich, T. D., Shukhratovna, K. F., & Abdullaevna, A. G. (2019). Urate regulation gene polymorphisms are correlated with clinical forms of coronary heart disease. International Journal of Pharmaceutical Research, 11(3), 198-202.
Махкамова Н. У. Эффективность комплексной терапии хронических цереброваскулярных расстройств у пациентов с артериальной гипертензией //Український хіміотерапевтичний журнал. – 2013. – №. 3-4. – С. 63-65.
Махкамова Н. У., Ходжаев А. И. Частота встречаемости и структура цереброваскулярных осложнений артериальной гипертонии у лиц узбекской национальности с различными полиморфизмами генов ангиотензинпревращающего фермента и аполипопротеина Е //Евразийский кардиологический журнал. – 2012. – №. 2. – С. 55-58.
