RIGHT VENTRICULAR DYSFUNCTION IN CORONARY HEART DISEASE: MODERN CONCEPTS OF THE PROBLEM AND METHODS OF DIAGNOSIS
Keywords:
ischemic heart disease, right ventricle, myocardial dysfunction, echocardiographyAbstract
Our current medicine has been struggling for many years and continues to deal with a decrease in morbidity in the world, and the result of this, as a rule, should be reflected in a decrease in the number of hospitalizations of patients and the financial costs of treatment. Achieving such results is possible with the help of early detection of signs of an unfavorable prognosis of diseases and the implementation of appropriate preventive measures.
One of such urgent medical and social problems of modern cardiology is coronary heart disease due to atherosclerotic lesions of the coronary bed [1]. This is due to its high prevalence, high rates of disability and mortality associated with this pathology. In particular, myocardial infarction (MI) is considered an insidious complication of this kind of disease.
Thus, according to European experts, 21% of men and 22% of women die as a result of coronary heart disease during the year, which is about 2 million deaths per year [2]. The survival prognosis of patients with MI largely depends on the severity of postinfarction remodeling and the degree of myocardial dysfunction, which are the basis for the development and progression of heart failure [3].
It should be noted that today, from a practical point of view, the hemodynamic characteristics of the left ventricle (LV) are the most in demand and the most studied, since this is the main chamber, directly dependent on the damage to the coronary arteries, and its functionality reliably determines the prospects for survival. Much less information has been received about right ventricular (RV) dysfunction and its role in the development of adverse effects. However, with the introduction into clinical practice of new possibilities for diagnosing cardiac imaging, dysfunction of the right sections, namely, the right ventricle, becomes the subject of further search for solutions to the above problems.
This review will consider the main aspects of the right ventricle, modern methods for diagnosing its dysfunction and the impact on prognosis.
References
Tashkenbaeva E.N., Rajabova N.T., Nasyrova Z.A., Kadirova F. Sh. Impact of lipid metabolism disorders and psychological risk factors on the development of cardiovascular disease among women of different age categories//Journal of Critical Reviews Vol:7, Issue: 12. 2020. P. 991-993
Кардиологический альманах – 2009 / Под ред. А.Н. Пархоменко. – К.: ООО «Издательский дом «Аванпост-Прим», 2009. – 235 с.
В.И. Целуйко, Т.А. Лозовая, Д.А. Кныш, О.В. Дерновая Особенности показателей гемодинамики и диастолической функции у больных с инфарктом миокарда задней стенки левого желудочка с вовлечением правого желудочка // Український кардіологічний журнал 6/2012, 68-75c.
Baumi M. Left ventricular hypertrophy: an overlooked cardiovascular risk factor // Clev. Clin. J. Med. – 2010. – Vol. 77, No6. – P. 381-387.
Starr Т et al , 1943 г, Donald D.Е, Essex Н.Е, 1954 г.
Cohn J.N., Guiha N.H., Broder M.I. et al. Right ventricular infarction. Clinical and hemodynamic features // Am. J. Cardiol. – 1974. – Vol. 33, No2. – P. 209-214.
Кубекова С.Ж., Жусупова Г.К и др. Структурно-функциональные изменения правых отделов сердца у пациентов с ишемической болезнью сердца//Биология и интегративная медицина No1 – январь-февраль (47) 2021 eISSN: 2181-8827
Kjaergaard J., Iversen K., Akkan D. et al. Predictors of right ventricular function as measured by tricuspid annular plane systolic excursion in heart failure // Cardiovasc. Ultrasound. – 2009. – Vol. 7. – P. 51.
Mann D., Zipes D., Libby P. et al. Braunwald ́s Heart Disease: a Textbook of Cardiovascular Medicine. – Еd. 10th. – Philadelphia, 2014. – 2040 р.
Larose E., Ganz P., Reynolds G., et al. Right ventricular dys- function assessed by cardiovascular magnetic resonance imaging predict poor prognosis late after myocardial infarction // J. Amer. Coll. Cardiology. – 2007. – Vol. 49. – P. 855–862.
Lorenz C.H., Walker E.S., Morgan V.L., Klein S.S., Graham Jr T.P. Normal human right and left ven- tricular mass, systolic function, and gender differen- ces bycine magnetic resonance imaging. J.Cardio- vasc. Magn. Reson. 1999; 1: 7–21. DOI: 10.3109/ 10976649909080829
Lang R.M., Bierig M., Devereux R.B., Flachskampf F.A., Foster E., Pellikka P.A. et al. Recommendations for chamber quantification: a report from the American Society of Echocardiography's Guidelines and Stan- dards Committee and the Chamber Quantifi cation Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology. J. Am. Soc. Echocardiogr. 2005; 18: 1440–63. DOI: 10.1016/j.echo. 2005.10.005
Dell'Italia L.J. The right ventricle: anatomy, physiolo- gy, and clinical importance. Curr. Probl. Cardiol. 1991; 16: 653–720. DOI: 10.1016/0146-2806(91)90009-y
Petitjean C., Rougon N., Cluzel P. Assessment of myocardial function: a review of quantification methods and results using tagged MRI. J. Cardio- vasc. Magn. Reson. 2005; 7: 501–16. DOI: 10.1081/ jcmr-200053610
Dell'Italia L.J. The right ventricle: anatomy, physiolo- gy, and clinical importance. Curr. Probl. Cardiol. 1991; 16: 653–720. DOI: 10.1016/0146-2806(91)90009-y
Brown G.F. Vascular pattern of myocardium of right ventricle of human heart. Br. Heart J. 1968; 30: 679–86. DOI: 10.1136/hrt.30.5.679
Haji S.A., Movahed A. Right ventricular infarction – diagnosis and treatment // Clin. Cardiol. – 2000. – Vol. 23. – P. 473-482.
Haupt H.M., Hutchins G.M., Moore G.W. Right ven- tricular infarction: role of the moderator band artery in determining infarct size. Circulation. 1983; 67: 1268–72. DOI: 10.1161/01.cir.67.6.1268
Opitz, Christian F., Marius M. Hoeper, J. Simon R. Gibbs, Harald Kaemmerer, Joanna Pepke-Zaba, J. Gerry Coghlan, Laura Scelsi et al. "Pre-capillary, combined, and post-capillary pulmonary hypertension: a pathophysiological continuum." Journal of the American College of Cardiology 68, no. 4 (2016): 368-378.
Vonk Noordegraaf A, Westerhof BE, Westerhof N. The Relationship Between the Right Ventricle and its Load in Pulmonary Hypertension. J Am Coll Cardiol 2017;69:236-43.
Howlett, J. G. Canadian Cardiovascular Society Consensus Conference guidelines on heart failure, update 2009: diagnosis and management of right- sided heart failure, myocarditis, device therapy and recent important clinical trials / J. G. Howlett, R.S. Mc. Kelvie, J. M. O. Arnold, et. al. // Can. J. Cardiol. - 2009. - Vol. 25(2) - P. 85-105.
Rosenkranz S, Howard LS, Gomberg-Maitland M, et al. Systemic Consequences of Pulmonary Hypertension and Right-Sided Heart Failure. Circulation 2020;141:678-93.
Сокольская Н.О., Копылова Н.С., Иванов А.В., Кокшенев И.В. Анатомия и функция правого желудочка. Этиология, патогенез и современные аспекты эхокардиографической оценки правожелудочковой недостаточности. Клиническая физиология кровообращения. 2020; 17 (4): 266–83. DOI: 10.24022/1814-6910-2020-17-4-266-283
Voelkel N.F., Quaife R.A., Leinwand L.A. et al. Right ventricu- lar function and failure: report of National Heart, Lung, and Blood Institute Working Group on Cellular and Molecular Mechanisms of Right Heart Failure // Circulation. – 2006. – Vol. 114. – P. 1883–1891.
Осетрова Ольга Анатольевна //Структурно - функциональное ремоделирование правого желудочка при множественном поражении коронарных артерий до и после хирургической реваскуляризации миокарда//Автореферат/Пермь 2018
Rallidis, L.S. Right ventricular involvement in coronary artery disease: role of echocardiography for diagnosis and prognosis / L.S. Rallidis, G. Makavos, P. Nihoyannopoulos // J. Am Soc. Echocardiogr. - 2014. - Vol. 27(3). - P. 223-229.
Сергеева Л.И., Кожура В.Л., Чурляев Ю.А. Формирование дисфунции правого желудочка при остром инфаркте миокарда и хронической сердечной недостаточности. Общая реаниматология. 2007;3(2):57-60. https://doi.org/10.15360/1813-9779-2007-2-131-146
Lopez????Sendon J., Lopez de Sa E., Delcan J. L. Ischemia right ventricular dysfunction. Cardiovasc. Drugs Ther. 1994; 8 (2): 393—406.
Goldstein J. A. Right heart ischemia: pathophysiology, natural history, and clinical management. Prog. Cardiovasc. Dis. 1998; 40 (4): 325—341.
Caplin J. The difficulties in assessing right ventricular function. Heart 10. 1996; 3: 322.
Адамян К.Г., Чилингарян А.Л., Тумасян Л.Р. Ремоде- лирование правого желудочка при инфарктах миокарда различной локализации // Кардиология. – 2010. – No 3. – С. 16–21.
Н.С. Бусленко, Ю.И. Бузиашвили, И.В. Кокшенева, Э.У. Асымбекова, О.М. Шерстянникова. Ремоделирование правых отделов сердца у больных ишемической болезнью сердца: клинико-патофизиологические корреляции. Кардиоваскулярная терапия и профилактика, 2005; 4(5)
Сумин Алексей Николаевич, Корок Е.В., & Архипов О.Г. (2017). Систолическая дисфункция правого желудочка у больных ишемической болезнью сердца: гендерные особенности. Клиническая медицина, 95 (10), 894-900.
Leibundgut G., Rohner A., Grize L., Bernheim A., Kessel-Schaefer A., Bremerich J. et al. Dynamic assessment of right ventricular volumes and function by realtime three-dimensional echocardiography: a comparison study with magnetic resonance imaging in 100 adult patients. J. Am. Soc. Echocardiogr 2010; 23: 116–26. DOI: 10.1016/j.echo.2009.11.016
Meyer P., Filippatos G.S., Ahmed M.I., Iskandrian A.E., Bittner V., Perry G.J. et al. Effects of right ventricular ejection fraction on outcomes in chronic systolic heart failure. Circulation. 2010; 121: 252–8. DOI: 10.1161/CIRCULATIONAHA.109.887570
Lang R.M., Badano L.P., Mor-Avi V., Afilalo J., Armstrong A., Ernande L. et al. Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J. Am. Soc. Echocardiogr. 2015; 28: 1–39.e14.
Rudski L.G., Lai W.W., Afilalo J., Hua L., Handschumacher M.D., Chandrasekaran K. et al. Guidelines for the echocardiographic assessment of the right heart in adults: a report from the American Society of Echocardiography endorsed by the European Association of Echocardiography, a registered branch of the European Society of Cardiology, and the Canadian Society of Echocardiography. J. Am. Soc. Echocardiogr. 2010; 23: 685–713. DOI: 10.1016/j.echo.2010.05.010
Anavekar N.S., Skali H., Bourgoun M., Ghali J.K., Kober L., Maggioni A.P. et al. Usefulness of right ventricular fractional area change to predict death, heart failure, and stroke following myocardial infarction (from the VALIANT ECHO Study). Am. J. Cardiol. 2008; 101 (5): 607–12. DOI: 10.1016/j.amjcard.2007. 09.115
71. Ghio S, Recusani F, Klersy C, Sebastiani R, Laudisa ML, Campana C, Gavazzi A, Tavazzi L. Prognostic usefulness of the tricuspid annular plane systolic excursion in patients with congestive heart failure sec- ondary to idiopathic or ischemic dilated cardiomyopathy. Am J Cardiol. 2000; 85:837–842.
72. Guazzi M, Bandera F, Pelissero G, Castelvecchio S, Menicanti L, Ghio S, Temporelli PL, Arena R. Tricuspid annular plane systolic excursion and pulmonary arterial systolic pressure relationship in heart failure: an index of right ventricular contractile function and prognosis. Am J Physiol Heart Circ Physiol. 2013;305:H1373–H1381. doi: 10.1152/ajpheart.00157.2013.
73. Ghio S, Guazzi M, Scardovi AB, Klersy C, Clemenza F, Carluccio E, Temporelli PL, Rossi A, Faggiano P, Traversi E, Vriz O, Dini FL; All Investigators. Different correlates but similar prognostic implications for right ventricular dysfunction in heart failure patients with reduced or preserved ejection fraction. Eur J Heart Fail. 2017;19:873–879. doi: 10.1002/ejhf.664.
74. Dini FL, Carluccio E, Simioniuc A, Biagioli P, Reboldi G, Galeotti GG, Raineri C, Gargani L, Scelsi L, Mandoli GE, Cannito A, Rossi A, Temporelli PL, Ghio S; Network Labs Ultrasound (NEBULA) in Heart Failure Study Group. Right ventricular recovery during follow-up is associated with im- proved survival in patients with chronic heart failure with reduced ejection fraction. Eur J Heart Fail. 2016;18:1462–1471. doi: 10.1002/ejhf.639.
75. Damy T, Kallvikbacka-Bennett A, Goode K, Khaleva O, Lewinter C, Hobkirk J, Nikitin NP, Dubois-Randé JL, Hittinger L, Clark AL, Cleland JG. Prevalence of, associations with, and prognostic value of tricuspid annular plane systolic excursion (TAPSE) among out-patients referred for the evaluation of heart failure. J Card Fail. 2012;18:216–225. doi: 10.1016/j.cardfail.2011.12.003.
Chockalingam A., Gnanavelu G., Alagesan R., Subramaniam T. Myocardial performance index in evaluation of acute right ventricular myocardial infarction. Echocardiography. 2004; 21 (6): 487–94. DOI: 10.1111/ j.0742-2822.2004.03139.x
Алехин М.Н. Ультразвуковые методы оценки деформации миокарда и их клиническое значение. М.: Видар, 2012. 88 с. [Alekhin M.N. Ultrasonic methods for assessing myocardial deformity and clinical significance. Moscow: vidar Publ.; 2012. 88 p. (In Russ.)]
Бокерия Л.А., Бусленко Н.С., Бузиашвили Ю.И., Кокшенева И.В., Можина А.А. Дисфункция миокарда правого желудочка при ишемической болезни сердца (анатомия, патофизиология, диагностика, клиническое значение в карди- охирургии). М.: Научный центр сердечно-сосудистой хирургии им. А.Н. Бакулева РАМН, 2010. 324 с. [Bokeriya L.A., Buslenko N.S., Buziashvili Yu.I., Koksheneva I.v., Mozhina A.A. The right ventricular myocardial dysfunction in ischemic heart disease (anatomy, pathophysiology, diagnosis, clinical significance in cardiac surgery). Moscow: A.N. Bakoulev Scientific Center for Cardiovascular Surgery Publ.; 2010. 324 p. (In Russ.)]
Roes S.D., Mollema S.A., Lamb H.J., van der wall E.E., de Roos A., Bax J.J. validation of echocardiographic two-dimensional speckle tracking longitudinal strain imaging for viability assessment in patients with chronic ischemic left ventricular dysfunction and comparison with contrast-enhanced magnetic resonance imaging. Am J Cardiol. 2009;104(3):312-7. https://doi.org/10.1016/j. amjcard.2009.03.040
Rudski L.G., Lai w.w., Afilalo J., Hua L., Handschumacher M.D., Chandrasekaran K., Solomon S.D., Louie E.K., Schiller N.B. Guidelines for the echocardiographic assessment of the right heart in adults: a report from the American Society of Echocardiography endorsed by the European Association of Echocardiography, a registered branch of the European Society of Cardiology, and the Canadian Society of Echocardiography. J Am Soc Echocardiogr. 2010;23(7):685-713; quiz 786-8. https://doi.org/10.1016/j. echo.2010.05.010
Ersboll M., Andersen M.J., valeur N., Mogensen U.M., Fakhri Y., Thune J.J., Møller J.E., Hassager C., Søgaard P., Køber L. Early diastolic strain rate in relation to systolic and diastolic function and prognosis in acute myocardial infarction: a two-dimensional speckle-tracking study. Eur Heart J. 2014;35(10):648-56. https://doi. org/10.1093/eurheartj/eht179
Pandat S, Nagaura T, Nair SG, et al. An association between right ventricular dysfunction and sudden cardiac death. Heart Rhythm 2020;17:169-74.
Sanders JL, Koestenberger M, Rosenkranz S, Maron BA. Right ventricular dysfunction and long-term risk of death. Cardiovasc Diagn Ther 2020; 10(5): 1646-1658. Doi: 10.21037/cdt-20-450
Tadic M, Pieske-Kraigher E, Cuspidi C, et al. Right ventricular strain in heart failure: Clinical perspective. Arch Cardiovasc Dis 2017;110:562-71.