EXCESSIVE DAYTIME SLEEPING AS A MARKER OF OBSTRUCTIVE SLEEP APNEA-HYPOPNEA SYNDROME IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Keywords:
excessive daytime sleeping, obstructive sleep apnea-hypopnea syndrome, chronic obstructive pulmonary diseaseAbstract
To study the frequency of excessive daytime sleepiness and its significance in the formation of obstructive sleep apnea-hypopnea syndrome (OSAHS) in 200 patients with chronic obstructive pulmonary disease, screening testing was conducted using unified techniques of the Epworth Daytime Sleepiness Assessment Scale (ESS) questionnaire and a specialized questionnaire for the primary detection of OAPS in modification A.M. Vane, T.S. Yeligulashvili (1998).
The results of the study noted in 75.5% of patients with COPD the condition of excessive daytime sleepiness significantly higher among patients with stage fourth stage of COPD in men (87.6%) and in women (88.5%). A moderate or high degree of probability of drowsiness or falling asleep was noted in 43.0% of cases "when sitting passively in public places (sitting in a theater, at a meeting, etc.)", in 39.0% - "reading while sitting in an armchair", in 47.4% - "while resting in bed during the day", in 40.0% - "as a passenger in a car while driving non-stop for at least an hour on a flat road," in 41.7% - "sitting in a calm atmosphere after lunch without alcohol consumption." Among COPD patients with excessive daytime sleepiness in 57.6% of cases, there is a high probability of a clinical diagnosis of obstructive sleep apnea-hypopnea syndrome, which is often accompanied by loud night snoring (96.7%), respiratory arrest during sleep (91.4%), morning headaches or feelings of not refreshing sleep in the morning (79.5%), phenomena of nocturnal polyuria and frequent night awakenings (70.2%) and an increase in body weight over the past 3-5 years (63.0%).
References
Вейн А.М., Елигулашвили Т.С., Полуэктов М.Г. Синдром апноэ во сне и другие расстройства дыхания, связанные со сном: клиника, диагностика, лечение. Москва, Эйдос Медиа. – 2002.
Кондрацки Д.П., Мартынюк К.И., Писаренко С.В. Хроническая обструктивная болезнь легких как причина временной нетрудоспособности//XXIV Национальный конгресс по болезням органов дыхания. Сб. тезисов, 2019.- 201.-с.164-165.
Писаренко Н.К., Кондрацки Д.П., Писаренко С.В. ХОБЛ как компонента неинфекционных заболеваний и причина смертности// XXIV Национальный конгресс по болезням органов дыхания. Сб. тезисов, 2019.- 200.-с.163-164.
Axson E.L., Bottle A., Cowie M.R., Quint J.K. Relationship between heart failure and the risk of acute exacerbation of COPD//Thorax. 2021:76(8):807-814.
Axson E.L., Sundaram V., Bloom C.I., Bottle A., Cowie M.R., Quint J.K.Temporal Trends in the Incidence of Heart Failure among Patients with Chronic Obstructive Pulmonary Disease and Its Association with Mortality//Ann Am Thorac Soc. 2020:17(8):939-948.
Barnes P.J. Endo-phenotyping of COPD patients//Expert Rev Respir Med. 2021:15(1):27-37
Bourbeau J., Echevarria C. Models of care across the continuum of exacerbations for patients with chronic obstructive pulmonary disease//Chron Respir Dis Jan-Dec 2020:17. doi: 10.1177/1479973119895457
Chervin R.D. Sleepiness, fatigue, tiredness, and lack of energy in obstructive sleep apnea //Chest. 2000:118 (2): 372 – 379.
Dal Negro R.W., Carone M., Cuttitta G., Gallelli L., Pistolesi M., Privitera S., Ceriana P., Pirina P., Balbi B., Vancheri C., Gallo F.M., Chetta A., Turco P. Prevalence and clinical features of most frequent phenotypes in the Italian COPD population: the CLIMA Study//Multidiscip Respir Med. 2021:1:16(1):790.
Flemons W.W., Whitelaw W.A., Mc Nicholas W.T. et al. Clinical features of obstructive sleep apnea syndrome// Breathing Disorders in Sleep. – London. – WB Saunders. – 2002:64 – 85.
Gottlieb D.J., Whitney C.W., Bonekat W.H. et al. Relation of Sleepiness to Respiratory Disturbance Index // Am. J. Respir. Crit. Care Med.1999:159(6):502 – 507.
Guilleminault C, Hoed D, Mitler M. Clinical overview of the sleep apnea syndromes. In: Guilleminault C, Dement W, editors. Sleep apnea syndromes. New York: Allan R Liss; 1978, p. 1-12
Hurst J.R., Siddiqui M.K., Singh B., Varghese P., Holmgren U., de Nigris E. A Systematic Literature Review of the Humanistic Burden of COPD//Int J Chron Obstruct Pulmon Dis. 2021:10(16):1303-1314.
Johansson H., Berterö C., Berg K., Jonasson L.L. To live a life with COPD - the consequences of symptom burden //Int J Chron Obstruct Pulmon Dis. 2019:14:905-909.
Lazic Z., Stankovic I., Milenkovic B., Zvezdin B., Hromis S., Jankovic S., Cupurdija V. Characteristics of COPD Phenotypes in Serbia// Int J Chron Obstruct Pulmon Dis. 2021:16:643-654.
Masror-Roudsary D., Nasrin Fadaee Aghdam, Rafii F., Baha R., Khajeh M., Mardani A. The Relationship between Experienced Respiratory Symptoms and Health-Related Quality of Life in the Elderly with Chronic Obstructive Pulmonary Disease//Crit Care Res Pract. 2021:55:642-75.
Mathioudakis A.G., Janssens W., Sivapalan P., Singanayagam A. Dransfield M.T., Jens-Ulrik Staehr Jensen, Vestbo J. Acute exacerbations of chronic obstructive pulmonary disease: in search of diagnostic biomarkers and treatable traits// Thorax. 2020:75(6):520-527.
Milgrew A.T., Ryan C.F., Fleetman J.A. et al. The impact of obstructive sleep apnea and daytime sleepiness on work limitation// Sleep Med 2007: 9: 42-53.
Owens R., Malhotra A. Sleep-disordered breathing and COPD: the overlap syndrome// Respir Care 2010: 55(10): 1333-1346.
Partinen M., Hublin C. Epidemiology of sleep disorders. In: Kryger MH, Roth T, Dement WC. Principles and practice of sleep medicine. W.B. Saunders, Philadelphia, PA, USA, 2011.
Stanford R.H., Engel-Nitz N.M., Bancroft T., Essoi B. The Identification and Cost of Acute Chronic Obstructive Pulmonary Disease Exacerbations in a United States Population Healthcare Claims Database//COPD. 2020:17(5):499-508.
Ulfberg J, Carter N, Edling C. Sleep-disordered breathing and occupational accidents// Scand J Work Environ Health 2000: 26: 237-242.
Vega-Sánchez Á.E., Téllez-Navarrete N.A., Pérez-Padilla R.Chronic obstructive pulmonary disease: perspectives for primary health care//Rev Invest Clin. 2019:71(1):55-63.
Yang K., Wu Y., Chen D., Liu S., Chen R. The Impact of Lung Function on Extra-Pulmonary Diseases and All-Cause Mortality in US Adult Population with and without COPD //Clin Epidemiol. 2020:12:997-1005.
Zatloukal J., Brat K., Neumannova K., Volal Kopeckyakova E., Hejduk K., Kocova E., KudelaО., Mich 8, Plutinsky M., Koblizek V. Chronic obstructive pulmonary disease - diagnosis and management of stable disease; a personalized approach to care, using the treatable traits concept based on clinical phenotypes. Position paper of the Czech Pneumological and Phthisiological Society//Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2020:164(4):325-356.
