COMORBID DESORDERS OF THE CARDIOVASCULAR SYSTEM AND QUALITY OF LIFE OF PATIENTS WITH CRONIC OBSTRUCTIVE PULMONARY DISEASE IN THE REPUBLIC OF BELARUS

Abstract

The relevance of the topic is undeniable. COPD is one of the 3 leading causes of death in the world. In this article comorbid cardiovascular disorders, including pulmonary hypertension, affecting the quality of life in patients with COPD, were studied in 45 patients. It was found that in patients with COPD the following disorders prevail: severe course of the disease, expiratory dyspnea, irreversible bronchial obstruction, airway emphysema, which is accompanied by chronic respiratory insufficiency.  In 14,8±4,5 years from the disease onset, COPD patients show signs of pulmonary hypertension, mean pulmonary artery pressure increases up to 32,1±1,2 mm Hg and more, accompanied by moderate gas exchange disorders. The progression of the disease (the number of exacerbations per year was 5.12±2.3 times) in patients with COPD is accompanied by a gradual decrease in the parameters of tolerance to physical activity and quality of life. Thus, the analysis of integral quality of life indicators in the main group revealed a significant decrease to 55.7±0.8% of physical and to 38.2±0.8% of mental quality of life components. Walked distance in 6-minute walking test in patients with COPD was 60,7±0,6% of proper, which was the ground for establishing moderate restrictions of mobility in patients with COPD and caused disability in about 50% of patients with COPD.