RESULTS OF OBSERVATIONS OF PERSONS WITH CORONAVIRUS ON THE PRIMARY LINE OF HEALTHCARE
Keywords:
SARS-CoV-2 coronavirus, COVID-19, patients infected with the SARS-CoV-2Abstract
The number of people infected with the SARS-CoV-2 coronavirus, which causes COVID-19, is growing worldwide. The emergence of a severe acute respiratory syndrome coronavirus 2, or SARS-CoV-2, against the background of coronavirus 2, causing Coronavirus disease 2019, or COVID-19, quickly increased into a pandemic. Given the fact that the disease is new, it is necessary to study the characteristics of the distribution and the clinical picture in persons who have had this disease. Based on the results of the practical work of the medical organization of primary health care in the context of a pandemic, analyze the distribution and clinical picture of the pathological process of COVID-19 in adult patients. The course of the disease was analyzed in the first 100 patients with confirmed COVID-19: 58 (58%) men and 42 (42%) women. In 11 (11%) patients examined by contact with a sick relative, the disease was asymptomatic; 89% had a mild course of COVID-19 with minor catarrhal symptoms. The largest group of patients who underwent COVID-19 were persons aged 30-55 years (65%): in 20% of cases, the patients were older than 65 years. During the COVID-19 pandemic, a large burden falls on outpatient doctors, because 80% of patients are asymptomatic or mild. Analysis of the clinical picture, data of laboratory parameters allows to diagnose and assess the severity of the disease as early as possible.
References
Всемирная организация здравоохранения. Рекомендации ВОЗ для населения в связи c распространением коронавирусной инфекции (COVID-19) [интернет]. — ВОЗ, 2020. [World Health Organization. Rekomendatsii VOZ dlya naseleniya v svyazi c rasprostraneniyem koronavirusnoy infektsii (COVID-19) [Internet]. WHO; 2020. (In Russ).] Доступно по: https://www.who.int/ru/emergencies/diseases/novel-coronavirus-2019/advice-for-public#. Ссылка активна на 16.04.2020.
Методические рекомендации Минздрава России «Профилактика, диагностика и лечение новой коронавирусной инфекции COVID-19» (версия 7 от 3.06.2020). / Metodicheskie rekomendat-sii Minzdrava Rossii «Profilaktika, diagnostika i lechenie novoj koronavirusnoj infektsii COVID-19» (versiya 7 ot 3.06.2020). [in Russian]
Report of the WHO-China Joint Mission on Coronavirus Disease 2019 (COVID-19). 16-24 February 2020. who-china-joint-mission-on-covid-19-final-report.pdf.
ACR Recommendations for the use of Chest Radiography and Computed Tomography (CT) for Suspected COVID-19 Infection. https://www.acr.org/Advocacy-and-Economics/ACR-Position-Sta-tements/Recommendations-for-Chest-Radiography-and-CT-for-Suspected-COVID19-Infection.
COVID-19 Treatment Guidelines Panel. Coronavirus Disease 2019 (COVID-19) Treatment Guidelines. National Institutes of Health. https://covid19treatmentguidelines.nih.gov.
He X., Lau E.H.Y., Wu P., et al. Temporal dynamics in viral shedding and transmissibility of COVID-19. Nature medicine. https://doi.org/10.1038/s41591-020-0869-5
Ferran M. Coronavirus tests are pretty accurate, but far from perfect. May 6, 2020. https://theconversation.com/coronavirus-tests-are-pretty-accurate-but-far-from-perfect-136671
Liu R., Liu X., Han H., et al. The comparative superiority of IgM-IgG antibody test to real-time reverse transcriptase PCR detection for SARS-CoV-2 infection diagnosis [Internet]. Infectious Diseases (except HIV/AIDS). 2020;. MedRxiv https://doi.org/10.1101/ 2020.03.28.20045765.
Interim Guidelines for COVID-19 Antibody Testing. https://www.cdc.gov/coronavirus/2019-ncov/lab/resources/anti-body-tests-guidelines.html
Adams E., Ainsworth M., Anand R., et al. Evaluation of antibody testing for SARS-CoV-2 using ELISA and lateral flow immunoassays. National COVID Testing Scientific Advisory Panel. MedRxiv https://doi.org/10.1101/2020.04.15.20066407.
Zhao J., Yuan Q., Wang H., et al. Antibody responses to SARS-CoV-2 in patients of novel coronavirus disease 2019. MedRxiv https://doi.org/10.1101/2020.03.02.20030189.
Tan W., Lu Y., Zhang J., et al. Viral Kinetics and Antibody Responses in Patients with COVID