ANEMIA DEVELOPING IN CHRONIC HEART FAILURE
Keywords:
chronic heart failure, anemia chronic pain, erythropoietin, iron deficiency anemia, oral and intravenous preparationsAbstract
In the last ten years, the prolongation of chronic heart failure (CHF) has increased significantly with age. V svyazi s etim pered cardiologiami i terapevtami vstaet ryad novykh voprosov pri vedenii pasititov s mnojestvennymi pututstvuyushchimi bololevaniyami, takimi kak anemiya i heart pathology.
Many attribute the leading role of the negative effect of anemia on CHF to iron deficiency (ID). Against the background of dyspepsia, energy metabolism decreases, mitochondrial dysfunction develops, and the production of heme-containing myoglobin protein is impaired, which leads to a decrease in myocardial function. Anemia, ID, and ID have been shown to be associated with left ventricular hypertrophy and dilation, decreased skeletal muscle and myocardial function, while normal iron levels are associated with increased endurance and aerobic capacity. According to other data, the presence or absence of anemia does not affect the unfavorable prognosis associated with ID. It is associated with increased mortality in patients with chronic heart failure. These data indicate that the presence of ID is associated with a less favorable prognosis than the presence of anemia [12]. Today, it is known that anemia that develops in connection with ID is a very negative condition for a patient with ID.
The research group under the leadership of Donalda Silverberg explained the "syndrome of cardiorenal anemia" in CHF and developed a principle that helped to introduce some changes and tactical treatment of patients [5]. In addition to that, the results of the recent researches are based on the analysis of some conclusions related to the pathogenesis and treatment of anemia in SBE, presented in the current overview.
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