FEATURES OF THE COURSE OF HYPOGONADOTROPIC HYPOGONADISM IN WOMEN (REVIEW OF LITERATURE)
Keywords:
Hypogonadism, pituitary adenoma, ovarian failure, menstruation, gonads, incidentalomaAbstract
In this article, we consider the features of the clinical course of hypogonadotropic hypogondism, its etiology and pathogenesis in women of reproductive age with inactive pituitary adenoma.
According to the literature, clinical manifestations of hypogonadotropic (or secondary) hypogonadism may be the first and only manifestations of hypothalamic-pituitary dysfunction in adult patients with various pituitary neoplasms. Knowledge of the features of the clinical manifestations of hypogonadism in this category of patients can help clinicians as an early diagnosis of a pituitary tumor.
References
Braun, M., Wassmer, G., Klotz, T., Reifenrath, B., Mathers, M., Engelmann, U.: Epidemiology of erectile dysfunction: results of the 'Cologne Male Survey'. International journal of impotence research 12(6), 305-311 (2000). doi:10.1038/ sj. ijir.3900622.
Chabbert-Buffet N, Skinne DC, Caraty A, et al. Neuroendocrine effect of progesterone// Steroids - 2000; 65:613-620.
Cheng K., Leung P. The expression, regulation and signal transduction pathway of the mammalian gonadotropin-releasing hormone receptor// Can J Physiol Pharmacol - 2000; 78:1029-1052.
Davey DA. Androgens in women before and after the menopause and post bilateral oophorectomy: clinical effects and indications for testosterone therapy. Womens Health (Lond Engl) 2012; 8 (4): 437–46.
Erichsen MM, Husebye ES, Michelsen TM et al. Sexuality and fertility in women with Addison's disease. J Clin Endocrinol Metab 2010; 95 (9): 4354–60.
Komm B.S., Terpening C.M., Benz N.J., et al. Estrogen binding, receptor mRNA, and biologic response in osteoblast-like osteosarcoma cells//Science - 1988-v.241: 81-84.
Kratz A, Ferraro M, Sluss P, Lewandrowski K. Laboratory reference values. N Engl J Med 2004, 351: 1548–63.
Lambalk CB. Treatment of WHO 1: GnRH or gonadotropins? In: Cohlen B, Van Santbrink E, Laven J, eds. Ovulation Induction – Evidence based guidelines for daily practice. Boca Raton: CRC Press; 2017:81-86.
Thornton JW, Evolution of vertebrate steroid receptors from an ancestral estrogen receptor by ligand exploitation and serial genome expansions// PNAS - 2001, 98 5671 5676.
Vogiatzi M. G. Hypogonadism // Medscape. — 2021.
Российское общество акушеров-гинекологов. Женское бесплодие: клинические рекомендации. — 2021. — 82 с.
Руководство по клинической эндокринологии. Под ред. Н.Т. Старковой - Питер Пресс, 1996, 544 стр.
