ЭПИКАРД ЁҒ ТЎҚИМАСИНИНГ ЮРАК-ҚОН ТОМИР КАСАЛЛИКЛАРИ ПАТОГЕНЕЗИДАГИ АҲАМИЯТИ (АДАБИЁТЛАР ТАҲЛИЛИ)
##article.subject##:
Эпикардиал ёғ тўқимаси, юрак етишмовчилиги, семизлик, магнит-резонанс томография##article.abstract##
Юрак-қон томир касалликлари жахонда ўлим ва ногиронликнинг асосий сабабидир. Сўнгги йилларда юрак висцерал ёғ қатлами - эпикард ёғ тўқимасининг юрак-қон томир касалликлари ривожланишидаги ролига қизиқиш тобора ортиб бормоқда [1]. Эпикард ёғ тўқимаси анатомик жиҳатдан миокард ва коронар артериялар билан бевосита боғлиқ бўлиб, у турли биологик фаол моддалар, жумладан яллиғланиш цитокинлари, адипокинлар ва оксидловчи стресс медиаторларини ишлаб чиқаради. Мазкур мақолада эпикард ёғ тўқимасининг морфологик ва функционал хусусиятлари, унинг метаболик ҳамда яллиғланиш жараёнларидаги иштироки, шунингдек, юрак-қон томир касалликлари билан боғлиқ клиник аҳамияти ҳамда текшириш усуллари ҳақидаги замонавий илмий маълумотлар таҳлил қилинган.
Библиографические ссылки
Antonopoulos, A. S., Papastamos, C., Cokkinos, D. V., Tsioufis, K., & Tousoulis, D. (2023). Epicardial adipose tissue in myocardial disease: from physiology to heart failure phenotypes. Current Problems in Cardiology, 48(10), 101841.
Arshi, B., Aliahmad, H. A., Ikram, M. A., Bos, D., & Kavousi, M. (2023). Epicardial fat volume, cardiac function, and incident heart failure: the Rotterdam study. Journal of the American Heart Association, 12(1), e026197.
Choy, M., Huang, Y., Peng, Y., Liang, W., He, X., Chen, C., ... & Wu, Y. (2023). Association between epicardial adipose tissue and incident heart failure mediating by alteration of natriuretic peptide and myocardial strain. BMC medicine, 21(1), 117.
Doesch, C., Haghi, D., Flüchter, S., Suselbeck, T., Schoenberg, S. O., Michaely, H., ... & Papavassiliu, T. (2010). Epicardial adipose tissue in patients with heart failure. Journal of Cardiovascular Magnetic Resonance, 12(1), 40.
Iacobellis, G. (2022). Epicardial adipose tissue in contemporary cardiology. Nature reviews cardiology, 19(9), 593-606.
Jin, X., Hung, C. L., Tay, W. T., Soon, D., Sim, D., Sung, K. T., ... & Lam, C. S. (2022). Epicardial adipose tissue related to left atrial and ventricular function in heart failure with preserved versus reduced and mildly reduced ejection fraction. European journal of heart failure, 24(8), 1346-1356.
Kenchaiah, S., Ding, J., Carr, J. J., Allison, M. A., Budoff, M. J., Tracy, R. P., ... & Bluemke, D. A. (2021). Pericardial fat and the risk of heart failure. Journal of the American College of Cardiology, 77(21), 2638-2652.
Mazurek, T., Zhang, L., Zalewski, A., Mannion, J. D., Diehl, J. T., Arafat, H., ... & Shi, Y. (2003). Human epicardial adipose tissue is a source of inflammatory mediators. Circulation, 108(20), 2460-2466.
Packer, M. (2018). Epicardial adipose tissue may mediate deleterious effects of obesity and inflammation on the myocardium. Journal of the American College of Cardiology, 71(20), 2360-2372.
Pugliese, N. R., Paneni, F., Mazzola, M., De Biase, N., Del Punta, L., Gargani, L., ... & Masi, S. (2021). Impact of epicardial adipose tissue on cardiovascular haemodynamics, metabolic profile, and prognosis in heart failure. European Journal of Heart Failure, 23(11), 1858-1871.
Rossi, V. A., Gruebler, M., Monzo, L., Galluzzo, A., & Beltrami, M. (2023). The different pathways of epicardial adipose tissue across the heart failure phenotypes: from pathophysiology to therapeutic target. International Journal of Molecular Sciences, 24(7), 6838.
Sacks, H. S., Fain, J. N., Holman, B., Cheema, P., Chary, A., Parks, F., ... & Samaha, J. (2009). Uncoupling protein-1 and related messenger ribonucleic acids in human epicardial and other adipose tissues: epicardial fat functioning as brown fat. The Journal of Clinical Endocrinology & Metabolism, 94(9), 3611-3615.
Sacks, H. S., & Fain, J. N. (2007). Human epicardial adipose tissue: a review. American heart journal, 153(6), 907-917.
Talman, A. H., Psaltis, P. J., Cameron, J. D., Meredith, I. T., Seneviratne, S. K., & Wong, D. T. (2014). Epicardial adipose tissue: far more than a fat depot. Cardiovascular diagnosis and therapy, 4(6), 416.
van Woerden, G., Gorter, T. M., Westenbrink, B. D., Willems, T. P., van Veldhuisen, D. J., & Rienstra, M. (2018). Epicardial fat in heart failure patients with mid‐range and preserved ejection fraction. European journal of heart failure, 20(11), 1559-1566.
Van Woerden, G., Van Veldhuisen, D. J., Manintveld, O. C., Van Empel, V. P., Willems, T. P., De Boer, R. A., ... & Gorter, T. M. (2022). Epicardial adipose tissue and outcome in heart failure with mid-range and preserved ejection fraction. Circulation: Heart Failure, 15(3), e009238.
van Woerden, G., van Veldhuisen, D. J., Westenbrink, B. D., de Boer, R. A., Rienstra, M., & Gorter, T. M. (2022). Connecting epicardial adipose tissue and heart failure with preserved ejection fraction: mechanisms, management and modern perspectives. European journal of heart failure, 24(12), 2238-2250.
Agababyan, I. R., Iskandarov, F. I., & Mukhtarov, S. N. (2019). The role of adipose tissue inflammation markers as a major factor in the development of arterial hypertension in patients with metabolic syndrome. In The priorities of the world science: experiments and scientific debate (pp. 25-30). (in Russ)
Agababyan, I. R., & Jabbarova, N. M. (2023). Statins in the treatment of non-alcoholic fatty liver disease. Zamonaviy fan va ta'lim yangiliklari xalqaro ilmiy jurnal , 1 (4), 104-116.(in Uzb)
Agababyan, I. R., Sh, S. S., & Ismoilova, Y. A. 35-1 (75) 2025-Agababyan IR, Sadykova Sh. Sh.-Assessment of the effectiveness of glp-1 agonists in nafld in women of different age groups. Журнал репродуктивного здоровья и уро-нефрологических исследований.-2022.-№3(2)-С.6-9.
Agababyan, I. R., & Sadykova, Sh. Sh. (2022). Pleiotropic effects of statins in non-alcoholic liver disease and non-alcoholic steatohepatitis. Recept , (2), 194-199. (in Russ)
Agababyan, I. R., Rakhmonova, N. Sh., & Sadykova, Sh. Sh. Early detection of glomerular filtration rate disorders depending on the degree of obesity Recipt, 2022(3) 310-315. (in Russ)
Rizaev A. Jhasur , Makhmonov S. Lutfulla , Gadaev G. Abdugaffor , Turakulov I. Rustam. Assessment of external factors involved in prediction of iron deficiency anemia associated with Helicobacter Pylori. Journal of Biomedicine and Practice. 2022, vol.7, issue 4, pp. 436-446
Rizaev , Zh ., & Yunuskhanova , K. (2021). Pathobiological interactions of rheumatoid arthritis and periodontal disease. Medicine and Innovation, 1(2), 37–40.
Mancia G, Kreutz R, Brunström M, et al. ESH Guidelines for the management of arterial hypertension. The Task Force for the management of arterial hypertension of the European Society of Hypertension: Endorsed by the International Society of Hypertension (ISH) and the European Renal Association (ERA). J Hypertens. 2023.
Nurmamatovich E. O., Makhammatkulovich R. N., Shavkatovna S. S. MARKER TNF-308G/A IN PATIENTS WITH RELATIVE BLADDER CANCER //World Bulletin of Public Health. – 2023. – Т. 28. – С. 95-97.
Shavkatovna S. S., Makhammatkulovich R. N. FEATURES OF SARCOPENIA IN CANCER PATIENTS //EUROPEAN JOURNAL OF MODERN MEDICINE AND PRACTICE. – 2024. – Т. 4. – №. 8. – С. 286-292.
Anisonyan, A. V., Sandler, Yu. G., Khaimenova, T. Yu., Keyan, V. A., Saliev, K. G., Sbikina, E. S., & Vinnitskaya, E. V. (2020). Non-alcoholic fatty liver disease and type 2 diabetes mellitus: issues of liver fibrosis diagnostics. Therapeutic archive , 92 (8), 73-78. (in Russ)
Yakhontov, D. A., Ostanina, Yu. O., & Lukinov, V. L. (2024). Features of the course of stable ischemic heart disease with borderline stenosis of coronary arteries depending on the thickness of epicardial adipose tissue. Complex Issues of Cardiovascular Diseases , 13 (1), 6-15. (in Russ)
