НЕЙРОСЕНСОР КАРЛИКДА КЛИНИК НАТИЖАЛАРНИНГ ПРЕДИКТОРЛАРИ
##article.subject##:
ТЮНК, иммунологик маркерлар, қулоқда шовқин, эшитиш қобилияти тикланиши, эрта даволаш##article.abstract##
Ушбу тадқиқотда беморларда кузатилган тўсатдан юзага келган нейросенсор карликнинг (ТЮНК) клиник, аудиологик ва иммунологик хусусиятлари ўрганилди. 2014 йил январь ойидан 2022 йил декабрь ойигача бўлган даврда 83 нафар госпитализация қилинган беморларнинг 84 қулоғидаги касаллик ҳолатлари ретроспектив таҳлил қилинди. Натижаларга кўра, ТЮНК асосан бир томонлама эшитиш қобилиятининг йўқолиши сифатида намоён бўлган, эркакларда кўпроқ учраган ва касалликнинг ўртача ёши 41,6 йилни ташкил этган. Иммунологик текширувларда 16 ва 6 беморда мос равишда IgE ва IgM антитаналари юқори даражада аниқланган. Тадқиқотнинг натижаларига кўра, эрта даволаш эшитиш қобилиятини тиклашда асосий прогностик омил бўлиб, қулоқдаги шовқиннинг мавжудлиги ҳам ижобий натижалар билан боғланган. Тадқиқотдан шуни тахмин қилиш мумкинки, вирусли инфекциялар ва иммун механизмлар ТЮНК патогенезида муҳим роль ўйнаши мумкин.
Библиографические ссылки
Chandrasekhar SS, Tsai Do BS, Schwartz SR, Bontempo LJ, Faucett EA, Finestone SA, Hollingsworth DB, Kelley DM, Kmucha ST, Moonis G, Poling GL. Clinical practice guideline: sudden hearing loss (update). Otolaryngology–Head and Neck Surgery. 2019 Aug;161(1_suppl):S1-45. https://doi.org/10.1177/0194599819859885
Kim SH, Kim SJ, Im H, Kim TH, Song JJ, Chae SW. A trend in sudden sensorineural hearing loss: data from a population-based study. Audiology and Neurotology. 2017;22(6):311-6. https://doi.org/10.1159/000485313
Kang WS, Yang CJ, Shim M, Song CI, Kim TS, Lim HW, Ahn JH, Park HJ, Chung JW. Prognostic factors for recovery from sudden sensorineural hearing loss: a retrospective study. Journal of audiology & otology. 2017 Apr;21(1):9. https://doi.org/10.7874/jao.2017.21.1.9
Nosrati-Zarenoe R, Arlinger S, Hultcrantz E. Idiopathic sudden sensorineural hearing loss: results drawn from the Swedish national database. Acta Oto-Laryngologica. 2007 Jan 1;127(11):1168-75. https://doi.org/10.1080/00016480701242477
Merchant SN, Adams JC, Nadol Jr JB. Pathology and pathophysiology of idiopathic sudden sensorineural hearing loss. Otology & Neurotology. 2005 Mar 1;26(2):151-60. https://doi.org/10.1097/00129492-200503000-00004
Oreskovic Z, Shejbal D, Bicanic G, Kekic B. Influence of lipoproteins and fibrinogen on pathogenesis of sudden sensorineural hearing loss. The Journal of Laryngology & Otology. 2011 Mar;125(3):258-61. https://doi.org/10.1017/S0022215110002252
Eisenhut M. Evidence supporting the hypothesis that inflammation-induced vasospasm is involved in the pathogenesis of acquired sensorineural hearing loss. International Journal of Otolaryngology. 2019 Nov 6;2019. https://doi.org/10.1155/2019/4367240
Greco A, Fusconi M, Gallo A, Marinelli C, Macri GF, De Vincentiis M. Sudden sensorineural hearing loss: an autoimmune disease?. Autoimmunity reviews. 2011 Oct 1;10(12):756-61. https://doi.org/10.1016/j.autrev.2011.05.005
Chadha S, Cieza A. Promoting global action on hearing loss: World hearing day. International journal of audiology. 2017 Mar 4;56(3):145-7. https://doi.org/10.1080/14992027.2017.1291264
Olusanya BO, Davis AC, Hoffman HJ. Hearing loss grades and the International classification of functioning, disability and health. Bulletin of the World Health Organization. 2019 Oct 10;97(10):725. https://doi.org/10.2471/BLT.19.230367
Kuhn M, Heman-Ackah SE, Shaikh JA, Roehm PC. Sudden sensorineural hearing loss: a review of diagnosis, treatment, and prognosis. Trends in amplification. 2011 Sep;15(3):91-105. https://doi.org/10.1177/1084713811408349
Karltorp E, Löfkvist U, Lewensohn‐Fuchs I, Lindström K, Eriksson Westblad M, Teär Fahnehjelm K, Verrecchia L, Engman ML. Impaired balance and neurodevelopmental disabilities among children with congenital cytomegalovirus infection. Acta Paediatrica. 2014 Nov;103(11):1165-73. https://doi.org/10.1111/apa.12745
Xie Y, Orabi NA, Zwolan TA, Basura GJ. Outcomes of unilateral idiopathic sudden sensorineural hearing loss: Two decades of experience. Laryngoscope Investigative Otolaryngology. 2019 Dec;4(6):693-702. https://doi.org/10.1002/lio2.331
Lee SY, Choi BY, Koo JW, De Ridder D, Song JJ. Cortical oscillatory signatures reveal the prerequisites for tinnitus perception: a comparison of subjects with sudden sensorineural hearing loss with and without tinnitus. Frontiers in Neuroscience. 2020 Nov 27;14:596647. https://doi.org/10.3389/fnins.2020.596647
Polatova Djamila , Madaminov Ahmad, Raximov Nodir . Significance of expression PD-L1 and p53 proteins in human papillomavirus-associated oropharyngeal squamous cellcarcinoma Journal of Biomedicine and Practice. 2022, vol . 7, issue 4, pp . 144-151
Chen C, Shi G, He M, Song X, Cheng X, Wang B, Gu H, Liang X, Yu S. Characteristics and prognosis of idiopathic sudden sensorineural hearing loss in aged people: a retrospective study. Acta Oto-Laryngologica. 2019 Nov 2;139(11):959-65. https://doi.org/10.1080/00016489.2019.1657589
