PERIODONTAL DISEASES AND THE RISK OF PREMATURE BIRTH: CLINICAL AND PREVENTIVE REVIEW
Keywords:
periodontitis, preterm birth, inflammation, pregnancy, prevention, microbiotaAbstract
This article explores the association between periodontal disease and the risk of preterm birth in women of reproductive age. Chronic inflammation and microbial invasion from the oral cavity may trigger systemic immune responses, increasing the likelihood of pregnancy complications. The article presents data on the prevalence of periodontitis, its pathophysiological effect on pregnancy, and current strategies for screening and prevention.
References
Petrova, L. A., & Ivanov, D. V. (2021). Хронический пародонтит как фактор риска преждевременных родов: патогенез и профилактика. Акушерство и гинекология, 9(2), 33–37.
Karimova, Z. N., & Rakhimova, G. U. (2020). Пародонтопатогены и их системное воздействие на течение беременности. Узбекский медицинский журнал, 11(3), 51–56.
World Health Organization. (2022). Oral health status report: Global trends and challenges. Geneva: WHO Publications.
Zhang, L., & Wang, Y. (2019). Association between periodontal disease and preterm birth: a meta-analysis. Journal of Maternal-Fetal & Neonatal Medicine, 32(4), 678–684.
Offenbacher, S., Barros, S. P., & Beck, J. D. (2018). Rethinking periodontal inflammation and pregnancy outcomes. Periodontology 2000, 78(1), 115–130.
Yoon, S. H., & Lee, M. K. (2020). Periodontal inflammation and reproductive health: cytokine mechanisms and clinical correlations. Reproductive Immunology Journal, 7(1), 102–109.
Khasanova, G. T., & Mamatova, N. R. (2021). Преждевременные роды: роль иммунного ответа на очаги хронического воспаления. Клиническая медицина Узбекистана, 14(2), 64–70.
Silva, M. J., & Dourado, M. M. (2022). Effectiveness of periodontal treatment in preventing adverse pregnancy outcomes: systematic review. BMC Pregnancy and Childbirth, 22(1), 1–10.
Smirnova, O. A., & Alexandrova, E. P. (2023). Стоматологический скрининг у беременных: значение в снижении перинатальных рисков. Российский журнал стоматологии, 29(1), 21–26.
American College of Obstetricians and Gynecologists. (2021). Oral health care during pregnancy and through the lifespan (Committee Opinion No. 569). Washington, DC: ACOG.
