CLINICAL AND IMMUNOLOGICAL FEATURES OF THE COURSE OF BRUCELLOSIS IN WOMEN OF FERTILE AGE

Authors

  • DJURAYEVA Kamola Stanislavovna
  • NIYAZOVA Tajigul Axmetovna

Keywords:

brucellosis, interleukins, fertile age

Abstract

60 sick women with various clinical forms of brucellosis were studied. It was established that the content of IL-4 and IL-6 in the peripheral blood of women with acute and chronic forms of brucellosis corresponds to indicators of the activity of the infectious process, which is confirmed by the Wright reaction indicators. The results obtained can be used to create a treatment algorithm for sick women with various clinical forms of brucellosis.

References

Belozerov E.S., Zmushko E.I. Organopathology in brucellosis / Zoonoses: Current problems in the clinic and experiment: Sat. scientific tr. 6th Rep. scientific-practical conf. – Makhachkala, 2000. – P.131-137. (in Russ).

Dzhuraeva K. S. et al. Clinical and epidemiological features of chronic brucellosis in women of fertile age based on materials from the city Regional Clinical Hospital. – 2022. (in Russ).

Dzhuraeva N. et al. Analysis of the clinical effectiveness of cycloferon and polyoxidonium in women of reproductive age with brucellosis. – 2022. (in Russ).

Dzhuraeva K.S., Niyazova T.A. CLINICAL COURSE OF BRUCELLOSIS IN AN ENDEMIC FOCUS IN WOMEN OF FERTILE AGE // Bulletin of the Tashkent Medical Academy No. 3/1 – P. 82-85 (in Russ).

Lobzin Yu.V. et al. Guide to Infectious Diseases. – St. Petersburg: Medicine, 2000. (in Russ).

Marupova M.D. Juraeva K.S., Niyazova T.A. STUDYING THE QUALITY OF LIFE IN WOMEN OF FERTILE AGE WITH CHRONIC BRUCELLOSIS WHO RECEIVED CYCLOFERON IN COMPLEX THERAPY//Biology va tibbiyot muammolari No. 3.1 (145) 2023 – P. 100-105(in Russ).

Niyazova T. A. Study of the quality of life in women of fertile age with chronic brucellosis who received cycloferon in complex therapy. – 2023. (in Russ).

Yushchuk N.D., Vengerov Yu.Ya. Lectures on infectious diseases. Volume 1. M.: VUNMTs, 1999.-454 p. (in Russ).

Yarmukhamedova N. A. et al. Clinical and epidemiological aspects of neurobrucellosis according to the regional infectious diseases clinical hospital of Samarkand // Bulletin of Science and Education. – 2020. – No. 18-2 (96). – P. 72-77. (in Russ).

Yarmukhamedova N. A. et al. Clinical and epidemiological aspects of neurobrucellosis according to the information of samarkand municipal infectious diseases hospital // Bulletin of science and education. – 2020. – No. 14-2. – pp. 61-66.

Yarmukhamedova N. A. et al. Modern aspects and the role of the cytokine status of the problem of brucellosis Abstract //International Scientific and Practical conference “COVID-19 and other topical infections of Central Asia” June 23-24, 2022, Shymkent. – 2022. – P. 172. (in Russ).

Golding B., Scott D.E., Scharf O.L., Huang L.Y., Zaitseva M., Lapham C. et al. Immunity and protection against Brucella abortus. Microbes Infect. 2001; 3(1): 43–8.

Skendros P., Boura P. Immunity to brucellosis. Rev. Sci. Tech. 2013; 32(1): 137–47.

Yakubovna E. M. et al. CHARACTERISTICS OF THE CLINICAL-EPIDEMIOLOGICAL TRANSITION OF BRUCELLOSIS IN WOMEN OF FERTILITY AGE ON THE BASIS OF THE MATERIALS OF THE HOSPITAL OF INFECTIOUS DISEASES OF KASHKADARYA REGION //JOURNAL OF BIOMEDICINE AND PRACTICE. – 2022. – T. 7. – No. 3. (in Uzb)

Yarmukhamedova N. A. et al. Clinical and epidemiological aspects of neurobrucellosis according to the information of samarkand municipal infectious diseases hospital //Infectious diseases. – 2020. – No. 3. – pp. 60-65.

Yarmukhamedova M. Q., Yakubova N. S., Juraeva K. S. Main modern aspects of neurobrucellosis according to the materials of the regional infectious clinical hospital of Samarkand city //Science and Education. – 2023. – T. 4. – No. 2. – pp. 509-515.

Статья поступила в редакцию 10.07.2024; одобрена после рецензирования 21.08.2024; принята к публикации 24.08.2024.

The article was submitted 10.07.2024; approved after reviewing 21.08.2024; accepted for publication 24.08.2024.

Информация об авторах:

Ниязова Тажигул Ахметовна - к.м.н., доцент Ташкентская медицинская академия, Ташкент, Узбекистан Е-mail: Niyazova_T@gmail.com, ORCID: 0009-0004-5467-8543

Джураева Камола Станиславовна - ассистент. Самаркандский государственный медицинский университет, Самарканд, Узбекистан. Е-mail: djuraevakamola1988@gmail.com, https://orcid.org/0000-0002-4171-1154

Источники финансирования: Работа не имела специального финансирования.

Конфликт интересов: Авторы декларируют отсутствие явных и потенциальных конфликтов интересов, связанных с публикацией настоящей статьи.

Вклад авторов:

Ниязова Т.А. — идеологическая концепция работы, написание текста; редактирование статьи;

Джураева К.С. — сбор и анализ источников литературы, написание текста.

Information about the authors:

Tajigul A. Niyazova — PhD, аssociate professor, Tashkent Medical Academy. Tashkent, Uzbekistan; E-mail: Niyazova_T@gmail.com, ORCID: 0009-0004-5467-8543

Kamola S. Djuraeva — Assistant. Samarkand state medical university. Samarkand, Uzbekistan; E-mail: djuraevakamola1988@gmail.com, https://orcid.org/0000-0002-4171-1154

Sources of funding: The work did not receive any specific funding.

Conflict of interest: The authors declare no explicit or potential conflicts of interest associated with the publication of this article.

Contribution of the authors:

Niyazova T.A. — ideological concept of the work, writing the text; editing the article;

Djuraeva K.S. — collection and analysis of literature sources, writing the text.

Published

2024-11-05