TROMBOFILIYA BILAN OG’RIGAN AYOLLARDA HOMILADORLIK VA TUG’RUQNING XUSUSIYATLARI FOLAT ALMASHINUVINING BUZILISHI BILAN BIRGALIKDA
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homiladorlik, tug’ruq, folat almashinuvi, trombofiliya##article.abstract##
Maqolada folat metabolizmi va trombofiliya buzilishlarida va ikkinchisining yo’qligida homiladorlik va tug’ruqning istiqbolli qiyosiy tahlili natijalari keltirilgan. Taqqoslangan ikkita guruhda qon oqimini dopplerometrik o’rganish, umumiy klinik va o’ziga xos laboratoriya tadqiqotlari o’tkazildi. shuningdek, trombofiliya va folat etishmovchiligi bo’lgan ayollarda homiladorlik kursining xususiyatlari va uning natijalarini baholashga imkon beradigan homiladorlik va tug’roq natijalarini dinamik kuzatish.
Homiladorlikning borishini baholash shuni ko’rsatdiki, trombofiliya va folat almashinuvi buzilgan har uchinchi bemorda abort qilish xavfi mavjud va har o’ninchi homiladorlikda intrauterin kechikish sindromi bilan murakkablashadi va gipertenziv kasalliklar o’rtacha har 20 holatda sodir bo’ladi. Shuningdek, asosiy guruhdagi ayollarda amniotik muhitning patologiyasi platsentaning erta pishishi, kam/polihidramnioz va dopplerometrik tekshiruvda ona-platsenta - homila tizimidagi qon oqimining buzilishi shaklida ustunlik qiladi, bu mos ravishda 23,3% va 42% ni tashkil qiladi.holatlar. Ushbu ko’rsatkichlar trombofil va folatga bog’liq anormalliklarni aniqlamagan bemorlarga nisbatan tadqiqot guruhidagi homiladorlikning ushbu asoratlaridan ancha yuqori.
Tug’ruq tahliliga ko’ra, taqqoslangan guruhlar o’rtasida tug’ruq davomiyligi va tug’ruq jarayonining asoratlari tabiati bo’yicha farqlar yo’q. Kesariy kesish qayta takrorlanishini tahlil qilish shuni ko’rsatdiki, asosiy guruh ayollarida qorin bo’shlig’i orqali tug’roq nazorat guruhidagi ayollarga qaraganda 3 baravar ko’p bo’lgan, bu asosan ona qornidagi homilaning noqulay holati, platsenta anomaliyalari (homilaning joylanishi) bilan bog’liq, shoshilinch tuqruqni talab qiladigan homilador ayollardagi gipertenziv kasalliklar.
Ikkala taqqoslangan guruhdagi yangi tug’ilgan chaqaloqlarning holatini baholash trombofiliya va folat almashinuvi buzilgan ayollarda yangi tug’ilgan chaqaloqlarda o’sish-vazn ko’rsatkichlarining pastligini aniqladi.
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