SURUNKALI BUYRAK KASALLIGIGA CHALINGAN BOLALARDA BUYRAK FAOLIYATINI BAHOLASHNING ZAMONAVIY USULLARI
##article.subject##:
anemiya, temir tanqisligi anemiyasi, surunkali buyrak kasalligi, glomerulyar filtratsiya##article.abstract##
Surunkali buyrak kasalligi (CBP) kasallikning oldindan aytib bo'lmaydigan kursi va o'z vaqtida tashxis qo'yish va davolash bo'lmaganda yuzaga keladigan asoratlar tufayli jiddiy sog'liqni saqlash muammosi hisoblanadi. Mavjud ma'lumotlarga ko'ra, 16 yoshgacha bo'lgan bolalarda CKDning terminal bosqichining o'rtacha kasallanish darajasi har yili 1 million bola populyatsiyasiga 1-3 holatni tashkil qiladi [1-4]. Bolalikda CKD bosqichlarini tashxislash va aniqlash mezonlari 2012 yilda KDIGO tomonidan moslashtirilgan [5]. Cbp tashxisi buyrak to'qimalarida qaytarilmas strukturaviy va morfologik o'zgarishlarning laboratoriya va instrumental belgilari mavjud bo'lganda, glomerulyar filtratsiya tezligi (GFR) 3 oy yoki undan ko'proq vaqt davomida 60 ml/min/1,73 m² dan pastga tushganda aniqlangan buyrak shikastlanishining klinik belgilariga asoslanadi. Bundan tashqari, biokimyoviy qon testlari (karbamid, kreatinin, karbamid azoti va boshqalar) va siydik sinovlari (leykotsituriya, eritrotsituriya, proteinuriya, albuminuriya va boshqalar)dagi o'zgarishlar.
Библиографические ссылки
Абдурасулов Ф. П., Юлдашев Б. А., Муродова М. Д. Коррекция гиперкоагуляционного синдрома у больных хроническом гломерулонефритом с нефротической формой //ТОМ–II. – 2019. – Т. 16. – №. 2. – С. 250.
Фейзуллаева Н. и др. Состояние сердечно-сосудистой системы и центральной гемодинамики при гломерулонефрите у детей //Журнал гепато-гастроэнтерологических исследований. – 2021. – Т. 2. – №. 3.2. – С. 21-26.
Вялкова, А. А., Зорин, И. В., Чеснокова, С. А., & Плотникова, С. В. (2019). Хроническая болезнь почек у детей. Нефрология, 23(5), 29-46. URL: https://cyberleninka.ru/article/n/hronicheskaya-bolezn-pochek-u-detey
Voronina T. et al. Study of the effect made by interval hypoxic training on cardiac metabolism and hemodynamics //Cardiometry. – 2021. – №. 20. – С. 8-9.
Levin, A., Stevens, P. E., Bilous, R. W., Coresh, J., De Francisco, A. L. M., De Jong, P. E., Griffith, K. E., Hemmelgarn, B. R., Iseki, K., Lamb, E. J., Levey, A. S., Riella, M. C., Shlipak, M. G., Wang, H., White, C. T., & Winearls, C. G. (2013). Kidney disease: Improving global outcomes (KDIGO) CKD work group. KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney International Supplements, 3(1), 1-150. https://doi.org/10.1038/kisup.2012.73
Pierce, C. B., Muñoz, A., Ng, D. K., Warady, B. A., Furth, S. L., & Schwartz, G. J. (2021). Age-and sex-dependent clinical equations to estimate glomerular filtration rates in children and young adults with chronic kidney disease. Kidney international, 99(4), 948-956. https://doi.org/10.1016/j.kint.2020.10.047.
Zou, L., Sun, L., Nicholas, S. B., Lu, Y., K, S. S., & Hua, R. (2020). Comparison of bias and accuracy using cystatin C and creatinine in CKD-EPI equations for GFR estimation. European Journal of Internal Medicine, 80, 29-34. https://doi.org/10.1016/j.ejim.2020.04.044
Stehlé, T., & Delanaye, P. (2024). Which is the best glomerular filtration marker: Creatinine, cystatin C or both? European Journal of Clinical Investigation, 54(10), e14278. https://doi.org/10.1111/eci.14278
Schwartz, G. J., Schneider, M. F., Maier, P. S., Moxey-Mims, M., Dharnidharka, V. R., Warady, B. A., Furth, S. L., & Muñoz, A. (2012). Improved equations estimating GFR in children with chronic kidney disease using an immunonephelometric determination of cystatin C. Kidney International, 82(4), 445-453. https://doi.org/10.1038/ki.2012.169
Fogo, A.B. Mechanisms of progression of chronic kidney disease. Pediatr Nephrol 22, 2011–2022 (2007). https://doi.org/10.1007/s00467-007-0524-0
Ng, D. K., & Pierce, C. B. (2021). Kidney Disease Progression in Children and Young Adults With Pediatric CKD: Epidemiologic Perspectives and Clinical Applications. Seminars in Nephrology, 41(5), 405-415. https://doi.org/10.1016/j.semnephrol.2021.09.002
