PNEVONIYASI BOR BOLALARDA O’PKA ENDOKRIN TIZIMINING ONTOGENEZI
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Ontogenez, bolalar, pnevmoniya, apudotsitlar, giperplaziya, gistologiya##article.abstract##
Inson o'pkasining embrional gistogenezi jarayonida apudotsitlarning erta morfofunksional differentsiatsiyasi kuzatiladi. Ushbu organning yallig'lanish patologiyasi bo'lgan yosh bolalarning o'pkasida endokrin tuzilmalar katta barqarorlik bilan aniqlanadi va ularning soni juda ko'p. Kasallik qancha uzoq davom etsa, bronxlar va nafas olish yo'llarida shuncha ko'p apudotsitlar va NETlar topiladi. Katta bronxlarda kichiklarga qaraganda ko'proq endokrin tuzilmalar mavjud. Postnatal ontogenezning dastlabki davrida yallig'lanishli o'pka kasalliklari apudotsitlar giperplaziyasi uchun predispozitsiya qiluvchi omil hisoblanadi.
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