ERKAKLARDA SPERMOGRAMMA KO'RSATKICHLARINING COVID-19 INFEKSIYASIDAN OLDIN VA KEYIN O'ZGARISHI TENDENTSIYALARI
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COVID-19, SARS-CoV-2, erkaklar fertilligi, erkaklarning reproduktiv tizimi##article.abstract##
Covid-19 bilan kasallangan bemorlarning spermogramma ko'rsatkichlari COVID-19 infektsiyasini boshdan kechirmagan bemorlarning ko'rsatkichlaridan sezilarli darajada farq qildi. Ularning eyakulyatsiya hajmi 2 baravar, sperma umumiy soni esa 3,6 baravar kam. Shunga ko'ra, sperma konsentratsiyasi deyarli 2 barobar kamayadi. Sperma suyuqligining pH darajasining oshishi aniqlanadi. Spermatozoidlarning patologik shakllarining ulushi 2 baravar yuqori bo'lib chiqdi.
20 yil oldingi ma'lumotlar bilan solishtirganda, sezilarli o'zgarishlar ro'y berganligi tasdiqlandi: sperma sonining sezilarli darajada kamayishi (COVID-19 bilan kasallangan bemorlarda 5 baravar va COVID-19 bilan kasallanmaganlarda 2,6 baravar), faol harakatlanuvchi sperma soni va harakatsiz sperma (1,8 baravar kamaygan va COVID-19 bilan kasallanganlarda mos ravishda 1,6 baravar ko'paygan).
Xulosa. Covid-19 bilan kasallangan va qon zardobida IgG SARS-CoV-2 darajasi yuqori bo'lgan erkaklar fertilligi sezilarli miqdoriy va sifat o'zgarishlari bilan ajralib turadi. Shu sababli, COVID-19 infektsiyasi erkaklarning reproduktiv funktsiyasiga ta'sir qiladi va shu bilan so'nggi o'n yilliklarda sodir bo'lgan erkaklar fertilligi pasayishiga yordam beradi. Ushbu ma'lumotlar mintaqada tug'ilishning soni pasayishini ko'rsatdi.
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