EFFECT OF INTRAOPERATIVE INTRAUTERINE CONTRACEPTION ON THE STATE OF HUMORAL IMMUNITY

Authors

  • Nasirova Zebiniso Azizovna
  • Negmadjanov Bahodur Boltaevich

Keywords:

cesarean section, contraception, IUD, immunity, cytokines, interleukin

Abstract

The effect of postplacental IUD administration on humoral immunity in women after cesarean section was studied in this research. 75 women  aged 22 to 37 years, who underwent  a cesarean section, were examined. Peripheral blood was taken on 5 th - 6th days after the surgery, in order to  study serum concentrations of main proinflammatory cytokines of immune system: IL-1β and IL-8. We have found a significant suppression of the serum concentration of IL-1β against the background of an increase in the production of IL-8, which is an important pro-inflammatory cytokine of a nonspecific link in immunity that immediately responds to the introduction of foreign materials into the body.

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Published

2021-05-30