ANTIFOSFOLIPID SINDROMI BILAN BOG‘LIQ ASOSIY AKUSHERLIK ASORATLARI (ADABIYOTLAR SHARHI)

##article.authors##

  • Zaripov Sh.Sh
  • Sultonova N.A
  • Zaripova D.Ya

##article.subject##:

AFS (antifosfolipid sindromi), bola tushishi, homiladorlik, tromboembolik asoratlar

##article.abstract##

AFS (antifosfolipid sindromi) organizm autoimmun reaksiyasining buzilishi bo‘lib, homiladorlik davrida homila tushishi, tromboembolik asoratlar ko‘rinishida namoyon bo‘ladi.  Bu akusherlik va perinatal asoratlarning yuqori xavfi bilan bog‘liq. U birinchi navbatda homila-yo‘ldosh tizimidagi qon aylanishiga ta’sir qiladi. Autoimmun reaksiyalar natijasida hosil bo‘lgan tromblar butun organizmdagi endoteliy devorlarini, xususan, yo‘ldosh va trofoblast tomirlaridagi kabi qon tomirlarini ham shikastlaydi, bu homilaning antenatal o‘limiga yoki homiladorlikning erta muddatlarida homila tushishiga olib kelishi mumkin.

Библиографические ссылки

Meroni P.L. et al. Pathogenesis of the antiphospholipid syndrome: an additional example of the mosaic of autoimmunity // Journal of Autoimmunity. 2018; 30(1-2): 99-103.

Erkan D., et al. Clinical patterns and outcomes in APS patients: multicenter cohort // Arthritis Rheum. — 2019. — Vol. 60, No. 4. — P. 1103–1111.

Hughes G.R. The anticardiolipin antibodies and the antiphospholipid syndrome // Ann. Rheum. Dis. — 2019. — Vol. 49, No. 5. — P. 289–293.

Pierangeli S.S., et al. Animal models of APS: lessons for pathogenesis // J. Thromb. Haemost. — 2017. — Vol. 5, No. 1. — P. 1–9.

Miyakis S., Lockshin M.D., Atsumi T., et al. International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome // Journal of Thrombosis and Haemostasis. — 2016. — Vol. 4, No. 2. — P. 295–306.

Galli M., Barbui T. Antiphospholipid antibodies and venous thromboembolism // Semin. Thromb. Hemost. — 2017. — Vol. 33, No. 7. — P. 645–651.

Ruiz-Irastorza G., Hunt B.J., Khamashta M.A. A systematic review of secondary thromboprophylaxis in patients with antiphospholipid antibodies // Arthritis & Rheumatism. — 2017. — Vol. 57, No. 8. — P. 1487–1495.

Negmatullaeva, M. N., Tuksanova, D. I., & Zaripova, D. Y. (2024). Structural-optical properties of blood serum and their role in predicting the development of osteoporosis in perimenopause. Russian Bulletin of Obstetrician-Gynecologist, 24(3), 71-76.Sacks G.P., et al. The role of complement in obstetric APS // Placenta. — 2014. — Vol. 35, No. 11. — P. 1–8.

Schreiber K., Hunt B.J. Managing antiphospholipid syndrome in pregnancy // Thrombosis Research. — 2019. — Vol. 181, Suppl. 1. — P.41–46.

Zaripova D.Ya., Abdullaeva M.A., Sultonova N.A., Ahmedov F.K., Nasirova Z.S., Umurov E.U., Shukrullaeva G.Zh. Optimizaciya mer diagnostiki rannej menopauzy i prezhdevremennoj menopauzy. Zhuranl Reproduktivnoe zdorov'e vo stochnaya Evropa. 2024;14 (5). S.617-628.

Tong M., et al. Trophoblast dysfunction and apoptosis associated with aPL // Hum Reprod Update. 2017. Vol. 21. P. 97–118.

Viall C.A., Chamley L.W. Placental infarction and impaired spiral artery remodeling in APS // Autoimmun Rev. 2019. Vol. 14. P. 446–471.

Zaripova, D.Ya., Abdullayeva, M. A., Sultanova, N. A., Akhmedov, F. K., Nasirov, Z. S., Umarov, E. U., & Shukrullayeva, G. J. (2024). Optimization of diagnostic measures for early menopause and premature menopause. The journal" Reproductive Health of Eastern Europe, 14(5), 617-628.

Willis R., et al. Pathophysiology of the antiphospholipid antibody syndrome // Autoimmunity Highlights. — 2021. — Vol. 2, No. 2. — P. 203-210.

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##submissions.published##

2026-05-02