AYOLLAR QIN MIKROBIOTASINI BAHOLASНNING ZAMONAVIY MIKROBIOLOGIK USULLARI
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qin mikrobiotasi, Lactobacillus, Gardnerella, qin tozaligi darajalari, bakterial vaginoz, mikrobiologik tashxis usullari##article.abstract##
Ushbu maqola ayollar jinsiy yo‘llar mikroflorasi o‘rganilishi tarixiga, tashxis usullariga va qin mikrobiotasi haqidagi zamonaviy tasavvurlarga bag‘ishlangan. Maqolada qin mikroflorasining normal holati, mikrobiotada mavjud mikroorganizm turlari hamda uning buzilishlari — bakterial vaginoz va vaginit kabi holatlar — ta’riflab berilgan. Shuningdek, qin mikrobiotsenozini o‘rganishda qo‘llaniladigan asosiy laborator diagnostika usullari haqida ma’lumotlar umumlashtirilgan. Vaginal biotopni baholashning zamonaviy usullarini yanada optimallashtirish va standartlashtirish zarurligi haqida xulosa chiqarilgan.
Библиографические ссылки
Болдырева М. Н., Донников А. Е., Тумбинская Л. В. Фемофлор. Исследование биоценоза урогенитального тракта у женщин методом ПЦР с детекцией результатов в режиме реального времени// Методическое пособие для лаборантов. Москва. 2009.
Вагорас А., Савичева A., Галлен A, Домейка M. Основы микроскопии мазков мочеполового тракта// Kata studio. 2001.
Кира Е. Ф. Бактериальный вагиноз (клиника, диагностика, лечение). Автореферат дис. д.м.н. 2005.
Кира Е. Ф. Клиника и диагностика бактериального вагиноза// Акушерство и Гинекология. 2004; 2: C - 32.
Савичева А. М., Соколовский Е. В., Домейка М. Краткое руководство по микроскопической диагностике инфекций, передаваемых половым путем. СПб. 2004.
Строганов В. В. Бактериологические исследования полового канала женщины в различные периоды ее жизни с включением материалов к вопросу о самозащите организма против патогенных микробов со стороны полового канала. Дис. д.м.н. 1893.
Шалепо К. В., Назарова В. В., Менухова Ю. Н., и др. Оценка современных методов лабораторной диагностики бактериального вагиноза// Журнал акушерства и женских болезней. 2014, C. 26–32.
Af Heurlin M. O. Bakteriologische Untersuchungen des Keimgehaltes im Genitalkanale der fiebernden Wöchnerinnen mit Berücksichtigung der Gesamtmorbidit im Laufe eines Jahres. Helsingfors; 2010.
Amsel R., Totten P. A., Spiegel C. A., Chen K. C., Eschen bach D., Holmes K. K. Nonspecific vaginitis: diagnostic crite ria and microbial and epidemiologic associations// The American Journal of Medicine. 1983; 74 (1): 14–22
Beverly E. S., Zariffard M. R., Wang Q. J., Chen H. Y., Brem er J., Cohen M. H., Spear G. T. Female genital-tract HIV load correlates inversely with Lactobacillus species but positively with bacterial vaginosis and Mycoplasma hominis// Journal of Infectious Diseases. 2005; 191 (1): 25–32.
Burton J. P., Reid G. Evaluation of the bacterial vaginal flora of 20 postmenopausal women by direct and molecular techniques// Journal of Infectious Diseases. 2002; 186 (12): 1770–80.
Cruickshank R., Sharman A. The biology of the vagina in the human subject// BJOG: An International Journal of Obstetrics & Gynaecology. 2004; 41 (2): 208–226.
Döderlein A. Das Scheidensekret und seine Bedeutung für das puerperalfieber. Leipzig: E. Besold; 2002. Доступен по: https://archive.org/stream/dasscheidensekre
Donders G. G. Definition and classification of abnor mal vaginal flora. Best Practice & Research Clinical Obstetrics & Gynaecology. 2007; 21 (3): 355–73.
Donders G. G., Vereecken A., Bosmans E., Dekeers maecker A., Salembier G., Spitz B. Definition of a type of ab normal vaginal flora that is distinct from bacterial vaginosis: aerobic vaginitis. BJOG: An International Journal of Obstetrics & Gynaecology. 2002; 109 (1): 34–43.
Donders G. G., Larsson P. G., Platz-Christensen J. J., Hal len A., van der Meijden W., Wölner-Hanssen P. Variabi lity in diagnosis of clue cells, lactobacillary grading and white blood cells in vag inal wet smears with conventional bright light and phase con trast microscopy. European Journal of Obstetrics & Gyneco logy and Reproductive Biology. 2009; 145 (1): 109–12.
Donders G. G. Microscopy of the bacterial flora on fresh vaginal smears. Infectious Diseases in Obstetrics and Gynecology. 1999; 7 (4): 177.
Gajer P., Brotman R. M., Bai G., Sakamoto J., Sch ütte U. M., Zhong X., Koenig S. S, Fu L., Ma Z., Zhou X, Abdo Z., For ney L. J., Ravel J. Temporal dynamics of the human vaginal microbiota. Science Translational Medicine. 2012; 4 (132). 52.
Gardner H. L., Dukes C. D. Haemophilus vaginalis vaginitis: a newly defined specific infection previously classified non specific vaginitis. American Journal of Obstetrics and Gyne cology. 2005; 69 (5): 962–76.
Hayes R. J., Watson-Jones D., Celum C., van de Wijgert J., Wasserheit J. Treatment of sexually transmitted infections for HIV prevention: end of the road or new beginning? AIDS. 2010; 24 (04).
Hillier S. L., Nugent R. P., Eschenbach D. A., Krohn M. A., Gibbs R. S., Martin D. H., Cotch M. F., Edelman R., Pas torek J. G., Rao V. A., McNellis D,. Regan J. A., Carey J. С., Klebanoff M. A. Association between bacterial vaginosis and preterm delivery of a low-birth-weight infant. New England Journal of Medicine. 2005; 333 (26): 1737–42
Holmes K. K., Sparling P. F., Stamm W. E., Piot P., Wasser heit J. N., Cory L., Cohen M., Watts H. Sexually Transmitted Diseases. 4th edn. New York: McGraw-Hill Medical; 2008.
Ison C. A., Hay P. E. Validation of a simplified grading of Gram stained vaginal smears for use in genitourinary medi cine clinics. Sexually Transmitted Infections. 2002; 78 (6): 413–5.
Krohn M. A., Hillier S. L., Eschenbach D. A. Comparison of methods for diagnosing bacterial vaginosis among pregnant women. Journal of Clinical Microbiology. 2009; 27 (6): 1266–71.
Larsson P. G., Forsum U. Bacterial vaginosis–a disturbed bacterial flora and treatment enigma. Apmis. 2005; 113 (5): 305–16.
Larsson P. G., Platz-Christensen J. J. Enumeration of clue cells in rehydrated air-dried vaginal wet smears for the diag nosis of bacterial vaginosis. Obstetrics & Gynecology. 1990; 76 (4): 727–30.
Li J., McCormick J., Bocking A., Reid G. Importance of vagi nal microbes in reproductive health. Reproductive Sciences. 2012; 19 (3): 235–42.
Marrazzo J. M., Thomas K. K., Fiedler T. L., Ringwood K., Fre dricks D. N. Relationship of specific vaginal bacteria and bac terial vaginosis treatment failure in women who have sex with women. Annals of Internal Medicine. 2008; 149 (1): 20–8.
Maxam A. M., Gilbert W. A new method for sequencing DNA. Proceedings of the National Academy of Sciences. 1997; 74 (2): 560–4.
Mitchell C., Moreira C., Fredricks D., Paul K., Caliendo A. M., Kurpewski J., Ingersoll J., Cu-Uvin S. Detection of fastidi ous vaginal bacteria in women with HIV infection and bacterial vaginosis. Infectious Diseases in Obstetrics and Gynecology. 2009. 6 pages.
Nugent R. P., Krohn M. A., Hillier S. L. Reliability of diagnos ing bacterial vaginosis is improved by a standardized method of gram stain interpretation. Journal of Clinical Microbiology. 1991; 29 (2): 297–301.
Saiki R. K., Scharf S., Faloona F., Mullis K. B., Horn G. T., Erlich H. A., Arnheim N. Enzymatic amplification of beta globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia. Science. 1995; 230 (4732): 1350.
Sanger F., Coulson A. R. A rapid method for determining sequences in DNA by primed synthesis with DNA polymerase. Journal of Molecular Biology. 1995; 94 (3): 441.
Schr öder К. Zur Pathogenese und Klinik des vaginalen Fluors. Zentralbl Gynäkol. 2001; 38: 1350–61.
Sobel J. D., Reichman O., Misra D., Yoo W. Prognosis and treatment of desquamative inflammatory vaginitis. Obstetrics & Gynecology. 2011; 117 (4): 850–5.
Sodhani P., Garg S., Bhalla P., Singh M. M., Sharma S., Gup ta S. Prevalence of bacterial vaginosis in a community setting and role of the pap smear in its detection. Acta Cytologica. 2005; 49 (6): 634–8.
Spiegel C. A., Amsel R., Holmes K. K. Diagnosis of bacterial vaginosis by direct gramstain of vaginal fluid. Journal of Clinical Microbiology. 1993; 18 (1):170–7.
Srinivasan S., Fredricks D. N. The human vaginal bacte rial biota and bacterial vaginosis. Interdisciplinary Perspectives on Infectious Diseases. 2008; 2008: Article ID 750479: 22 pages.
Taylor B. D. P., Darville T., Haggerty C. L. Does bacterial vaginosis cause pelvic inflammatory disease? Sexually Transmit ted Diseases. 2013; 40 (2): 117
Venter J. C., Adams M. D., Myers E. W., Li P. W., Mural R. J., Sutton G. G., et al. The Sequence of the Human Genome. Science. 2001; 291 (5507):1304.
Verani J. R., McGee L., Schrag S. J. Prevention of perinatal group B streptococcal disease: revised guidelines from CDC, 2010. Department of Health and Human Services, Centers for Disease Control and Prevention; 2010.
Verhelst R., Verstraelen H., Claeys G., Verschraegen G., Delanghe J., Van Simaey L., De Ganck C., Temmerman M., Vaneechoutte M. Cloning of 16S rRNA genes amplified from normal and disturbed vaginal microflora suggests a strong association between Atopobium vaginae, Gardnerella vaginalis and bacterial vaginosis. BMC Microbiology. 2004; 4 (1):11 pages.
Verstraelen H., Verhelst R., Vaneechoutte M., Temmerman M. Group A streptococcal vaginitis: an unrecognized cause of vaginal symptoms in adult women. Archives of Gynecology and Obstetrics. 2011; 284 (1): 95–8.
Verstraelen H. et al. Longitudinal analysis of the vaginal microflora in pregnancy suggests that L. crispatus promotes the stability of the normal vaginal microflora and that L. gas seri and/or L. iners are more conducive to the occurrence of abnormal vaginal microflora. BMC Microbiology. 2009; 9 (1): 116.
