TEMIR TANQISLIGIDA 6 OYLIK OQ ZOTSIZ KALAMUSHLARDA BUYRAK MORFOLOGIYASI
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temir tanqisligi, buyrak strukturasi, glomerulyar koptokcha gipertrofiyasi, tubulointerstitsial remodelizatsiya, oksidlovchi stress, morfometriya##article.abstract##
Mazkur tadqiqot temir tanqisligining 6 oylik oq zotsiz erkak kalamushlar buyraklarining morfologik va morfometrik ko‘rsatkichlariga ta’sirini o‘rganishga bag‘ishlangan. Tajribaviy modelda 3 oy davomida temir tanqisligi ozuqasi ishlatildi, umumgistologik va morfometrik tekshiruvlar o‘tkazildi. Natijalarda olib keluvchi va olib ketuvchi arteriolalarning kompensator ravishda kengayishi, glomerulyar tuzilmalarning gipertrofiyasi, Shumlyanskiy–Boumen kapsulasi bo‘shlig‘ining kengayishi hamda kapsuladagi bazal membrananing qalinlashuvi qayd etildi. Proksimal va distal burama naychalar epiteliy qavati balandligining sezilarli pasayishi, naychalar bo‘shliqlarining kengayishi va interstitsial to‘qimada dastlabki fibroz belgilari aniqlandi. Glomerulyar zichlikning kamayishi nefronlarning umumiy soni o‘zgarmagan holda qayd etildi. Olingan natijalar temir yetishmovchiligi buyrak shikastlanishining gipoksik-metabolik turini shakllanishiga olib kelishini, shuningdek erta tubulointerstitsial remodelizatsiya rivojlanishini isbotlaydi.
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