СУРУНКАЛИ БУЙРАК ЕТИШМОВЧИЛИГИДА РЕНИН-АНГИОТЕНЗИН ТИЗИМИНИНГ МОЛЕКУЛЯР-ГЕНЕТИК ХУСУСИЯТЛАРИНИ ТАҲЛИЛ ҚИЛИШ
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сурункали буйрак касаллиги, ренин- ангиотензин тизими, молекуляр генетик омиллар##article.abstract##
Мақолада сурункали буйрак етишмовчилиги (СБЕ) бўлган беморларда АГТР1 ва АГТР2 генларининг полиморфизми натижалари келтирилган. 153 та СБЕ беморлари орасида ўтказилган молекуляр-генетик таҳлил, ренин-ангиотензин тизими фаолияти билан боғлиқ генларнинг бир нуқтали полиморфизмларининг частотасининг ошишига мойиллик текширилди. СБЕ нинг ривожланиши АGTR 1 генининг С аллели ва АGTR 2 генининг Г аллели билан боғлиқ ҳолда кузатилмоқда.
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