SEMIZLIK BILAN OG'RIGAN BOLALARDA YURAK-QON TOMIR TIZIMIDAGI ENDOTELIYNING FUNKSIONAL HOLATI
##article.subject##:
semizlik, bolalar, endotelial disfunktsiya, yurak-qon tomir tizimi.##article.abstract##
Maqsad: ortiqcha vaznli va semiz bolalarda yurak-qon tomir tizimining endotelial disfunktsiyasi belgilarini aniqlash. Materiallar va usullar: 8 yoshdan 16 yoshgacha bo'lgan 52 nafar ekzogen konstitutsiyaviy semirib ketgan bolalar va o'smirlar har tomonlama tekshirildi. Natijalar: Endotelial disfunktsiyani o'rganishda tan olingan belgilarning ko'pligi aniqlandi: taqqoslash guruhiga nisbatan semirib ketgan va yurak-qon tomir tizimidagi o'zgarishlar bo'lgan guruhda albuminuriya (AU), endotelin-1 (ET-1), fon Villebrand omili (VWF) faolligi va IL-6 darajalari. Shuningdek, semirishda adiponektin sekretsiyasining pasayishi aniqlandi. Xulosa. Endotelial disfunktsiya va metabolik sindrom bir-biri bilan chambarchas bog'liq bo'lib, metabolik va yurak-qon tomir kasalliklariga olib keladigan uzluksiz tsiklni tashkil qiladi.
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