CLINICAL, IMMUNOLOGICAL AND GENETIC RESEARCH IN PATIENTS WITH DEVELOPMENTAL DEFECTS
Keywords:
cardiorenal syndrome, chronic kidney disease, heart failure, clinical-immunological and genetic studyAbstract
Cardiorenal syndrome (CRS), along with its associated conditions of chronic kidney disease (CKD) and heart failure (HF), remains one of the most pressing issues in global medicine today. The following statistical indicators are based on international and local data. According to statistics, on a global scale, approximately 30-50% of patients with heart failure also experience impaired renal function (cardiorenal syndrome). To achieve our objective, 156 patients with the pathology of "heart failure concurrent with chronic kidney disease," who were treated at the Bukhara branch of the Republican Specialized Scientific and Practical Medical Center for Emergency Medicine in 2025-2026, were included in this research study.
References
Thiele H., Akin I., Sandri M. PCI strategies in patients with acute myocardial infarction and cardiogenic shock // N Engl J Med. -2017. -V.377. - P.2419-2432.
Ibanez B., James S., Agewall S. ESC guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: the task force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC) // Eur Heart J. - 2018. - V.39. - P.119-177.
Levy B., Bastien O., Benjelid K. Experts’ recommendations for the management of adult patients with cardiogenic shock // Ann Intensive Care. - 2015. - V.5. - P.52.
Katz J.N., Stebbins A.L., Alexander J.H. Predictors of 30-day mortality in patients with re- fractory cardiogenic shock following acute myocardial infarction despite a patent infarct artery // Am Heart J. - 2009. - V.158. - P.680-687.
Prondzinsky R., Hirsch K., Wachsmuth L. et al. Vasopressors for acute myocardial infarction complicated by cardiogenic shock // Med Klin Intensivmed Notfmed. - 2017 Dec 4 [Epub ahead of print].
