PROGNOSTIC VALUE OF FERROKINETIC INDICATORS IN PATIENTS WITH HEPATITIS C IN ASSOCIATION WITH CHRONIC HEART FAILURE

Abstract

The study included 110 patients, of which the first group consisted of 32 patients with chronic viral hepatitis C and anemia without CHF, the second group consisted of 78 patients with chronic hepatitis C, CHF and anemia. 50 practically healthy people made up the control group. Results. The results of the analysis of the severity of anemia in patients of the first group showed that mild anemia was observed in 28.1% of patients, moderate anemia was detected in 50% of patients and severe anemia was observed in 21.9% of patients. A comparative analysis of the erythropoietin index, calculated using laboratory markers for the diagnosis of chronic inflammatory anemia, showed that the amount of erythropoietin in patients of group 2 was 1.19 times higher than in group 1, and an inverse, significant difference was found between these two indicators correlation connection. Conclusions. According to the analysis of ferrokinetic parameters in patients of group 1, anemia in this condition is characterized by chronic inflammation. But noteworthy points were observed in patients of group 2, that is, in this group, the serum iron content and erythropoietin index were high, which indicated the presence of unidentified aspects in the pathogenesis of the development of anemia in patients.