D-GIPOVITAMINOZNING TISH IMPLANTATSIYASI PAYTIDA ASORATLARNING CHASTOTASI VA XAVFIGA TA'SIRI
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D vitamini etishmovchiligi, osseointegratsiya, tish implantlari, regeneratsiya, suyak almashinuvi, mineral muvozanat##article.abstract##
Hozirgi vaqtda butun dunyo bo'ylab D vitamini tanqisligining ortishi haqida xabarlar mavjud.D vitamini faol D vitamini hosil qilish uchun osteoklastlar tomonidan sintezlanishi mumkin. Shu nuqtai nazardan, asosiy osteoklast transkripsiya omili bo'lgan NFATc1 ekspressiyasining ortishi kuzatilishi mumkin. Efrin-b2 kontsentratsiyasi, osteoklast sintez omili ham ortadi. Shu bilan birga, 25-gidroksivitamin D ning mavjudligi osteoklastlar tomonidan suyak rezorbsiyasini kamaytiradi. D-gipovitaminozi dental implantlarning yo'qolishiga olib kelishi mumkin. Implantatsiya yuzasini vit bilan singdirish ko'rsatilgan. D intraosseous qo'llashdan oldin kortikal suyak yo'qotilishini kamaytiradi va implant-suyak aloqasini 10% ga oshiradi.
D vitamini etishmovchiligi peri-implant suyak darajasining pasayishiga ta'sir qiladi, bunday bemorlarda operatsiya kunida D vitaminini qo'llash va D gipovitaminozini 25-gidroksixolekalsiferol bilan davolash implantatsiya paytida peri-implant suyak darajasining oshishiga ijobiy ta'sir ko'rsatdi. osseointegratsiya. D vitamini tanqisligi bo'lgan bemorlarga nisbatan D vitamini darajasi yuqori bo'lgan bemorlarda dental implantlarning yanada muvaffaqiyatli terapiyasi va yaxshilangan osseointegratsiyasini kutish mumkin.
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