ЧАҚАЛОҚЛАР ВА ЭРТА ЁШДАГИ БОЛАЛАРДА БИЛИРУБИН ЭНЦЕФАЛОПАТИЯСИДА УЧРАЙДИГАН АСОСИЙ НЕВРОЛОГИК СИНДРОМЛАР
##article.subject##:
илирубинли энсефалопатия, неонатал сариқлик, мия ярим палси, морбид, керниктерус##article.abstract##
Янги туғилган чақалоқларда сариқликнинг патологик курси замонавий дунёда долзарб муаммо ҳисобланади. Гипербилирубинемия
билан миянинг чуқур илдизларида билирубиннинг умумий миқдорини тўплаш табиати тўлиқ аниқланмаган. Бугунги кунга келиб,
билирубин энсефалопатиясининг клиникаси ва прогнози чуқур ўрганилмоқда. Билирубиннинг тўпланиши натижасида базал ганглионлар,
гипоталамус, мия поясининг ядролари (масалан, окуломотор, кохлеар, вестибуляр ядролар) ва мия сариқ рангга эга бўлади. Янги туғилган
чақалоқларнинг сариқлиги ўткир билирубинли энсефалопатия туфайли морбид ва преморбид ҳолатларни келтириб чиқаради, асоратлар
натижасида хорио-атетоид мия ярим палси кузатилади. Нейрон некрози ва базал ганглионлар ва мия сопи ядроларидаги нейронларнинг
сарғайиши натижасида юзага келадиган патологик ҳолат қайд этилади
Библиографические ссылки
Correspondence: Tina M Slusher Division of Global Health, Pediatric Intensive Care Faculty, Hennepin County Medical Center, University of Minnesota, 701 Park Ave, G7, Minneapolis, M
Division of Neuropathology, University of Alberta and Stollery Children’s Hospital, Edmonton, AB T6G 2B7, Canada; vanlande@ualberta.ca
Olusanya BO, Osibanjo FB, Mabogunje CA, Slusher TM, Olowe SA. The burden and management of neonatal jaundice in Nigeria: a scoping review of the literature. Niger J Clin Pract. 2016;19(1):1–17.
Bhutani VK, Zipursky A, Blencowe H, et al. Neonatal hyperbilirubinemia and Rhesus disease of the newborn: incidence and impairment estimates for 2010 at regional and global levels. Pediatr Res. 2013;74 .Suppl 1:86–100.
Burke BL, Robbins JM, Bird TM, Hobbs CA, Nesmith C, Tilford JM. Trends in hospitalizations for neonatal jaundice and kernicterus in the United States, 1988–2005. Pediatrics. 2009;123(2):524–532.
Ebbesen F, Andersson C, Verder H, et al. Extreme hyperbilirubinaemiain term and near-term infants in Denmark. Acta Paediatr.2005;94(1):59–64.
Bhutani VK, Johnson L. Kernicterus in the 21st century: frequently asked questions. J Perinatol. 2009;29 Suppl 1:S20–S24.
Brooks JC, Fisher-Owens SA, Wu YW, Strauss DJ, Newman TB. Evidence suggests there was not a “resurgence” of kernicterus in the 1990s. Pediatrics. 2011;127(4):672–679.
Ebbesen F, Bjerre JV, Vandborg PK. Relation between serum bilirubin
levels ≥450 μmol/L and bilirubin encephalopathy; a Danish populationbased study. Acta Paediatr. 2012;101(4):384–389.
Sgro M, Campbell DM, Kandasamy S, Shah V. Incidence of chronic bilirubin encephalopathy in Canada, 2007–2008. Pediatrics. 2012;130(4): e886–e890.
Williams O, Gbadero D, Edowhorhu G, Brearley A, Slusher T, Lund TC. Glucose-6-phosphate dehydrogenase deficiency in Nigerian children. PLoS One. 2013;8(7):e68800.
Owa JA, Ogunlesi TA. Why we are still doing so many exchange blood
transfusion for neonatal jaundice in Nigeria. World J Pediatr. 2009;5(1) :51–55.
Arain YH, Bhutani VK. Prevention of Kernicterus in South Asia: role
of neonatal G6PD deficiency and its identification. Indian J Pediatr.
;81(6):599–607.
Adebami O. Factors associated with the incidence of acute bilirubin encephalopathy in Nigerian population. J Pediatr Neurol. 2011;9(20):347–353.
Hansen TW. Pioneers in the scientific study of neonatal jaundice and kernicterus. Pediatrics. 2000;106(2):E15.
