БЕЗОВТА ОЁҚЛАР СИНДРОМИНИНГ ГЕНЕТИК АСПЕКТЛАРИ
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безовта оёқлар синдроми, генетика, Виллис—Экбом касаллиги, уйқудаги оёқлардаги даврий харакатлар##article.abstract##
Безовта оёқлар синдроми (БОС), шунингдек, Экбом синдроми сифатида ҳам танилган, уйқу ва хотиржам уйғониш пайтида пайдо бўладиган сенсо-мотор аломатлар билан тез-тез учрайдиган ҳаракат бузилиши. БОСнинг бирламчи ва иккиламчи шакллари мавжуд. Бирламчи БОСнинг асосий сабаби номаълум, аммо ирсий таъсирлар БОС патогенезида муҳим рол ўйнайди, айниқса касаллик ёшлигида бошланганда. Ушбу шарҳ мақоласида БОС эпидемиологияси, этиологияси, клиник кўринишлари, диагностик мезонлари батафсил кўриб чиқилган ва ушбу касалликнинг генетик жиҳатларига алоҳида эътибор берилади, чунки бизнинг олдинги тадқиқотларимизда БОС ҳолатларининг 40% дан ортиғи оилавий анамнезга эгалиги кузатилган. БОС ривожланишида иштирок этиши мумкин бўлган генлар таъкидланган.
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